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In this case report, researchers described a patient with Cushing's Disease exhibiting no detectable mass, where Metyrapone therapy was effectively used to manage symptoms, suggesting a treatment option for similar diagnostic challenges.

This case report details a diagnosis of adult-onset isolated hypogonadotropic hypogonadism in a 23-year-old African American female, highlighting its genetic basis and treatment approach.

This study found that women with PCOS have higher activity of the enzyme 5alpha-reductase, which may contribute to their elevated androgen levels.

This study reports a case of a woman with Cushing's disease whose initial complaint was hair loss, a rare presenting symptom, despite multiple dermatological signs like easy bruising and violaceous striae being more indicative of the condition.

This case report describes a pregnant woman diagnosed with Cushing Syndrome, likely due to an adrenal tumor, whose condition worsened during hospitalization, resulting in heart failure, sepsis, and shock.

This study found that basal serum cortisol levels are not significantly related to the form or duration of vitiligo in patients, suggesting their inadequacy in diagnosing subclinical adrenal insufficiency.

This study found that older beef feedlot steers had higher hair cortisol concentrations, but liver abscess presence was not linked to stress-related parameters in feedlot cattle.

In this case report, authors described a pet golden hamster with a confirmed adrenocortical adenocarcinoma, where laboratory testing and diagnostic imaging enabled antemortem diagnosis, despite the species' rarity for these procedures.

This case report suggests that genetic evaluation for glucocorticoid resistance, such as the NR3C1 gene variant, is crucial for proper diagnosis and management of patients showing atypical signs of hypercortisolism.

This study concluded that wedge resection in patients with polycystic ovary syndrome did not significantly affect androgen status or the biochemical features of the condition, though most regained regular menstrual cycles and some became pregnant.

Darker hair may lead to higher cortisol readings, suggesting a need to adjust for hair color in studies.

In this study, university students given open-label placebo treatment reported reduced psychological distress and lower hair cortisol concentrations during stressful exams, suggesting that these placebos may help manage the physiological and psychological impacts of prolonged stress.

This study found that patients with alopecia areata had significantly higher serum T3 and cortisol levels compared to healthy controls, although both remained within normal ranges, highlighting potential hormonal involvement in the condition. However, no significant differences were observed in T4 and TSH levels.

This study found that hair testosterone concentrations show some consistency over time, but factors like hair washing and individual growth rates influence these levels, suggesting the need for careful sampling and analysis adjustments.

This letter to the editor raises the possibility of a new medical entity characterized by symptoms such as poikiloderma, hyperpigmentation, alopecia, malformed bones, lymphedema, and decreased cortisol, but provides no clinical results.

This case study highlights the complexity of managing PCOS and its symptoms in transmen, suggesting hormonal fluctuations may lead to symptomatic relief with low dose estradiol.

This study suggests that measuring cortisol levels in hair may serve as a useful biomarker for assessing mood in individuals with bipolar disorder over recent months.

This study reported that pulverizing hair samples significantly improves the precision of testosterone measurement, with higher testosterone concentrations observed in men than in women.

This article provides guidelines for molecular genetic testing of congenital adrenal hyperplasia due to 21-hydroxylase deficiency, focusing on quality requirements, methodologies, and variant classification; it reports no new clinical results.

This study discusses the potential of targeting 11β-HSD1 for treating metabolic syndrome and highlights emerging promising data from human trials on selective 11β-HSD1 inhibitors.

This study found that a testosterone patch and gel showed bioequivalent testosterone levels in hypogonadal men, but the patch mimicked a natural circadian profile, while the gel resulted in higher dihydrotestosterone levels.

This review examines age-related changes in androgen levels in women and explores the rationale for testosterone replacement therapy, but it reports no new clinical findings.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

In this study, a plasma-fluorescent corticoid test effectively differentiated patients with adrenal insufficiency from those with normal adrenal function based on their response to corticotropin.

This article reviews the limited evidence on testosterone therapy for premenopausal women and notes a lack of long-term safety and effectiveness data for this population.

This study found that men with early-onset androgenetic alopecia and certain risk factors may have worse gonadal steroidogenesis and an increased likelihood of developing gonadal dysfunction, suggesting a male equivalent of polycystic ovarian syndrome.

This case report describes a 60-year-old postmenopausal woman with virilization and hirsutism caused by hilus-cell hyperplasia, which was confirmed following bilateral salpingo-oophorectomy.

This study found that sampling hair for cortisol analysis in mother-toddler dyads living in low-income U.S. homes is feasible, with 66% of approached dyads participating.

This case report describes the first instance of facial and oral mucosal hyperpigmentation and acanthosis nigricans linked to testosterone therapy in a patient with idiopathic hypogonadotropic hypogonadism.

In this review and meta-analysis, the authors concluded that 5α-reductase inhibitor therapy is not consistently associated with significant increases in serum testosterone levels in men.