TLDR A pregnant woman with Cushing Syndrome got worse and sadly passed away.
A 32-year-old pregnant woman at 24-25 weeks was diagnosed with Cushing Syndrome, likely due to an adrenal tumor, after presenting with symptoms such as weakness, amenorrhea, bruising, and hair loss. Physical examination revealed characteristic features like a full moon face and buffalo hump. Laboratory tests showed glucose intolerance, hypokalemia, elevated plasma cortisol levels, and decreased plasma ACTH. Despite 22 days of hospitalization, her condition deteriorated, leading to heart failure, sepsis, and shock.
86 citations
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October 2017 in “Translational pediatrics” Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.
67 citations
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September 2008 in “Dermatologic therapy” Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.
September 2022 in “Dermato” Adult acne is often related to hormonal disorders, especially in women, and may need long-term treatment involving specialists.
9 citations
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April 2020 in “Endocrinology, diabetes & metabolism case reports” Pregnancy with Cushing's syndrome is rare and risky for both mother and baby, needing early diagnosis and treatment.
November 2022 in “The Journal of Clinical Endocrinology and Metabolism” Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.
26 citations
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March 2014 in “Arquivos Brasileiros De Endocrinologia E Metabologia” The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.