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Glossary Cushing's syndrome

condition caused by excessive cortisol, leading to weight gain and skin changes

Cushing's syndrome, also known as hypercortisolism, is a condition characterized by prolonged exposure to high levels of cortisol, a hormone produced by the adrenal glands. This can result from taking corticosteroid medications or from the body producing too much cortisol due to tumors in the pituitary or adrenal glands. Symptoms include weight gain, particularly around the abdomen and face, thinning skin, easy bruising, and in some cases, hair loss or excessive hair growth.

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Research

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research Cushing Syndrome from Percutaneous Absorption of 1% Hydrocortisone Ointment in Netherton Syndrome

42 citations , January 2007 in “Pediatric dermatology”

This report describes an 11-year-old boy with Netherton syndrome who developed Cushing syndrome after using low-potency hydrocortisone ointment extensively, highlighting caution with long-term topical treatments in such conditions.

research Toward a Diagnostic Score in Cushing's Syndrome

42 citations , November 2019 in “Frontiers in Endocrinology”

This article provides an overview of diagnosing Cushing's syndrome, emphasizing the importance of assessing clinical signs and the appropriate use of first-line biochemical screening.

research [Cushing syndrome during pregnancy. New diagnostic methods used in 3 cases of adrenal cortex carcinoma].

10 citations , December 1992 in “PubMed”

This report of three cases found that diagnosing hypercortisolism during pregnancy can be challenging, but early detection using unbound steroid levels and MRI could prevent severe complications.

research An Interesting Case of Cushing Syndrome

1 citations , July 2024 in “International Journal of Innovative Science and Research Technology (IJISRT)”

In this case report, a 36-year-old woman was diagnosed with iatrogenic Cushing Syndrome caused by topical steroid use, leading to skin ulcers, diabetes, and anemia. Her condition improved after discontinuing the steroids and receiving appropriate treatment.

research Iatrogenic Cushing Syndrome and Secondary Adrenal Insufficiency Due to an Interaction Between Fluticasone and Ritonavir

1 citations , May 2021 in “Journal of the Endocrine Society”

This case report describes a woman with HIV who developed iatrogenic Cushing syndrome and adrenal insufficiency due to the interaction between fluticasone and ritonavir, highlighting the need for careful management of corticosteroid use in patients on protease inhibitors.

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community Minoxidil permanent face changes?

4 upvotes 4 years ago

Excessive use of topical minoxidil led to unwanted facial changes and side effects. The user plans to switch to oral minoxidil with microneedling for hair regrowth.

community I have not seen a single person who claims dutasteride destroyed their hair post a picture of the before/after

in Finasteride/Dutasteride 123 upvotes 2 years ago

The conversation discusses skepticism around claims that dutasteride worsens hair loss, with some users suggesting misinformation or panic during shedding as reasons for such claims. One user shared their negative experience with dutasteride, including increased sebum production and hair loss, and is now considering a higher dose of oral minoxidil after stopping dutasteride.

community Low cortisol it is due the fin

7 upvotes 1 year ago

The user has been taking 1mg finasteride daily for a year with no improvement in hair loss and reports low cortisol levels, sleep issues, and anxiety changes. The conversation includes discussions on the potential effects of finasteride on cortisol and neurosteroids, with suggestions to consult a doctor and consider other factors.

community There’s nothing better on the horizon [RANT]

22 upvotes 1 month ago

There is skepticism about new hair loss treatments, with the belief that current options like minoxidil, finasteride, and hair transplants are the best available. Concerns are raised about the systemic side effects of androgen-related treatments, even those marketed as topical, and doubts about the effectiveness of emerging treatments like clascoterone.

community Breezula is the final brick in the wall

36 upvotes 2 months ago

Breezula is discussed as a potential topical anti-androgen treatment for hair loss, with mixed opinions on its effectiveness and side effects compared to other treatments like finasteride, minoxidil, and RU58841. Some users express skepticism about its long-term efficacy and potential side effects, while others are hopeful for its approval and use in combination with existing treatments.

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