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GlossaryCushing's syndrome

condition caused by excessive cortisol, leading to weight gain and skin changes

Cushing's syndrome, also known as hypercortisolism, is a condition characterized by prolonged exposure to high levels of cortisol, a hormone produced by the adrenal glands. This can result from taking corticosteroid medications or from the body producing too much cortisol due to tumors in the pituitary or adrenal glands. Symptoms include weight gain, particularly around the abdomen and face, thinning skin, easy bruising, and in some cases, hair loss or excessive hair growth.

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community Medications that cause extra hair growth

in Research/Science 123 upvotes 1 year ago

The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

community Breezula will hit the market in 2026, Cosmo Pharmaceuticals statement!

in Product 52 upvotes 8 months ago

Breezula, a hair loss treatment, is expected to cost around $100 a month and is anticipated to be released in 2026. The effectiveness of Breezula is debated, with some suggesting it loses effectiveness over time and others arguing it maintains hair compared to baseline.

community 1.5 years on fin/min progress pics, thoughts would be great!

in Progress Pictures 69 upvotes 3 years ago

A 42-year-old male shared his 1.5-year hair regrowth progress using 1.25mg finasteride daily and regular doses of minoxidil twice a day, and recently started using the Derminator 2. He also mentioned his battle with cancer and Cushing's syndrome, which affected his weight and hair.

community Second update: almost 3.5 months min microneedling 1.5mm once a week ketoconazole shampoo 4 times a week

in Update 585 upvotes 2 years ago

A user's hair loss treatment regimen, which includes minoxidil, ketoconazole shampoo and microneedling; some participants questioned the results due to previous posts about hair transplants, but others agreed that quick results are possible with certain treatments.

community [25, F] [RANT] Shedding since March 2020. This just isn’t fair.

in Female 42 upvotes 3 years ago

User "missbloombastic" has been experiencing hair loss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hair loss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hair loss.

community My Dad seems to get his hair back?

in Question 15 upvotes 5 years ago

A user's father, mostly bald for 20 years, is regrowing hair using a serum called "Skrzypovita Serum Pro" without minoxidil. The user is curious about which ingredients might be causing hair growth.

community I have not seen a single person who claims dutasteride destroyed their hair post a picture of the before/after

in Finasteride/Dutasteride 123 upvotes 6 months ago

The conversation discusses skepticism around claims that dutasteride worsens hair loss, with some users suggesting misinformation or panic during shedding as reasons for such claims. One user shared their negative experience with dutasteride, including increased sebum production and hair loss, and is now considering a higher dose of oral minoxidil after stopping dutasteride.

community 1 yr on fin, min & dermaroller

in Progress Pictures 490 upvotes 2 years ago

User Clay1211 shared 1-year progress using finasteride, minoxidil, and dermaroller for hair loss. Commenters expressed surprise and praised the impressive results.

community 60-day progress with Minoxidil

in Progress Pictures 876 upvotes 9 months ago

A user shared a 60-day progress update on hair regrowth using only 5% Minoxidil foam once daily. Others suggested adding finasteride to address the underlying cause of hair loss and maintain long-term results.

community Quick rant for those on the fence.

in Chat 179 upvotes 1 year ago

The conclusion of the conversation is that the user regrets not starting finasteride earlier to treat their hair loss. They are currently using dutasteride, oral minoxidil, and RU58841. Other users in the conversation express frustration with fearmongering about finasteride and emphasize the benefits of starting treatment early.

community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 2 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community 1 Year Finasteride Update (pictures in comments)

in Finasteride 86 upvotes 6 years ago

The user shared a 1-year update on using finasteride (0.25mg three times a week), biotin, ketoconazole shampoo, and vitamin D for hair loss, showing positive results with pictures and no side effects. Other users commented on the effectiveness and the user's good response to the treatment.

community Why is it so hard to select one

in Satire 635 upvotes 1 week ago

Choosing hair loss treatments is challenging due to concerns about side effects from finasteride and minoxidil. Users suggest starting with topical treatments and gradually increasing dosage, while some recommend oral finasteride for its effectiveness despite potential side effects.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 127 upvotes 4 months ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community Another clueless guy fearmongering and spreading misinformation

in Chat 251 upvotes 9 months ago

The conversation discusses hair loss treatments, with some users advocating for finasteride and minoxidil, while others express concerns about potential side effects of finasteride. A social media influencer is criticized for promoting scalp massages and minoxidil over finasteride, which some believe is misinformation.

community Finasteride won’t make all your problems go away

in Finasteride/Dutasteride 323 upvotes 11 months ago

A user shared that while finasteride improved their hair, it didn't solve all their insecurities, suggesting that self-acceptance is key. Others in the conversation expressed varying opinions, with some feeling that finasteride significantly boosted their confidence and quality of life, while others acknowledged it as a solution to hair loss but not a cure-all for other personal issues.

community C’est terrible - at my wits end

in Female 449 upvotes 1 year ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community Starting Spironolactone, any ladies in here with experience or success?

in Female 56 upvotes 1 year ago

A female user starting Spironolactone treatment for thinning hair, and others sharing their experiences with Minoxidil and oral/sublingual Minoxidil as treatments.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 191 upvotes 2 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community 14 year old struggling with hair loss

in Treatment 9 upvotes 3 years ago

A 14-year-old is experiencing significant hair loss and was prescribed Aminexil by a dermatologist. They are concerned about potential side effects.

community Currently crushing 3 (5mg) tablets of fin into my topical min. Anyone do the same? If so how much do you add.

in Treatment 186 upvotes 6 months ago

The conversation discusses using crushed finasteride tablets mixed with topical minoxidil for hair loss treatment. Users share their experiences and opinions on the effectiveness and proper concentration of this method.

community Thinking of crushing bicalutamide/spiro or any other test suppressant in my topical fin min mix. What do yall think?

in Treatment 3 upvotes 1 year ago

The conversation is about adding crushed bicalutamide or spironolactone to a topical mix with finasteride and minoxidil to suppress testosterone in hair follicles, similar to what RU58841 does. The user cannot obtain RU58841 in their country and is seeking advice on this alternative approach for hair loss treatment.

community Goku was probably crushing his DHT with dut

in Satire 497 upvotes 2 years ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Users joke about Goku from Dragon Ball Z and his receding hairline.

community Zix in stemoxydine

in Treatment 6 upvotes 3 years ago

User considers making Zix topical solution with ethanol/alcohol for hair loss treatment. Asks if crushing b6 and zinc into stemoxydine is possible.

community Topical bicalutamide vs ru58841

in Female 1 upvotes 2 months ago

A user is seeking advice on making a topical bicalutamide solution as an alternative to RU58841 for hair loss, while already using dutasteride and minoxidil. They are considering crushing bicalutamide pills and adding them to their minoxidil.

community Does melatonin dissolve in isopropyl alcohol

in Technology 6 upvotes 1 year ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

community UPDATE (29 Male) 1.25mg oral fin (16 Months) and 5mg oral min (6 Months)

in Finasteride/Dutasteride 156 upvotes 6 months ago

A 29-year-old male has been using 1.25mg oral finasteride for 16 months and 5mg oral minoxidil for 6 months to treat hair loss. The replies indicate positive feedback on the treatment's results.

community What melatonin product are you using? Are you making your own solution?

in Product 3 upvotes 2 months ago

The conversation is about using melatonin for hair loss, with users discussing different products and methods for topical application. They mention concerns about ingredients and cost, and one user suggests a magnesium scalp serum with melatonin.

community Finasteride and minoxidil Dec 1st to may 10th

in Is this regrowth? 392 upvotes 6 months ago

The conversation is about someone's progress with hair regrowth using finasteride and minoxidil from December 1st to May 10th. They also mention using a topical treatment with a concentration of 0.004 per spray.

community 1.5 Month Photo Update in Similar Light

in Progress Pictures 82 upvotes 1 year ago

The post and conversation are about a user's hair loss progress after 1.5 months of using topical finasteride, minoxidil, a dermaroller, and various oils/supplements. The responses are positive, noting visible improvement and encouraging continued use for even better results.