September 2025 in “Cellular and Molecular Biology” This systematic review suggests that intraoperative corticosteroids can reduce postoperative edema in FUE hair transplantation donor areas, but highlights a need for more mechanistic studies to improve understanding of tissue regeneration.
September 2017 in “Journal of Investigative Dermatology” This study found that hyaluronic acid increased the size and cell proliferation of mixed aggregates in a 3D culture model, indicating its role in human hair follicle germ-like structure formation without enhancing dermal papilla cell markers.
September 2017 in “Journal of Investigative Dermatology” This study found that dermal papilla cells exhibit stage-dependent variation in histone methylation during the hair follicle cycle and display distinct chromatin marker expression when transitioning to in vitro culture.
September 2017 in “Journal of Investigative Dermatology” In this study, low-dose 453 nm blue light appeared to enhance hair growth by interacting with specific photoreceptors in the outer root sheath cells.
September 2017 in “Journal of Investigative Dermatology” This study found that Bone morphogenetic proteins (BMPs) play a crucial role in dermal papilla cells' ability to induce hair follicle stem cell differentiation, and that androgens may impair this process by downregulating BMPs.
72 citations
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January 2001 in “Drugs” This review discusses current and emerging drug therapies for treating androgenetic alopecia and alopecia areata, and reports no clinical results; it highlights a need for improved and novel treatments.
49 citations
,
August 2016 in “Aesthetic Surgery Journal” This study found that micro-needling with cosmeceuticals or platelet-rich plasma significantly improved wrinkles, skin laxity, scar softening, and hair growth over 12 months, with minimal side effects, and that the best results occur with pigment and platelet massaging between 5 to 30 minutes post-treatment.
45 citations
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January 2014 in “International Journal of Trichology” This study found that low-level laser therapy may improve hair growth in patients with androgenetic alopecia, either as a standalone treatment or combined with minoxidil or finasteride, without reported adverse reactions.
42 citations
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January 2021 in “Journal of Clinical Medicine” This review discusses advancements in the use of microneedle arrays and nanoparticles for transdermal delivery of therapeutics, noting challenges in overcoming the skin barrier and summarizing recent clinical trial achievements in areas like cancer therapy and gene therapy.
31 citations
,
September 2014 in “Journal of Pharmaceutical Sciences” This study found that Er–YAG laser treatment significantly enhanced skin absorption and follicular delivery of antialopecia drugs, suggesting a potential laser-assisted approach to treat alopecia.
31 citations
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November 2013 in “Dermatologic Clinics” This article discusses the use of a robotic system for hair graft harvesting in hair restoration surgery, focusing on its capabilities and the advantages and disadvantages, but it reports no new clinical findings.
29 citations
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July 2009 in “Journal of Dermatology” This study confirmed that 5% topical minoxidil is more effective than 1% in increasing hair density in Japanese men with androgenetic alopecia, with no significant difference in adverse event rates.
27 citations
,
August 2015 in “Experimental Dermatology” In this study, electrical stimuli at low voltage and frequency settings promoted hair growth in vitro and in rabbit models, possibly by activating pathways like Wnt/β-catenin.
13 citations
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January 2016 in “Burns & Trauma” This review discusses the effects of vacuum massage on skin structures and concludes that there is insufficient evidence for its efficacy in treating burn scars, suggesting more research is needed on its potential benefits and mechanisms.
12 citations
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July 2020 in “International Journal of Pharmaceutics” This study found that finasteride- and dutasteride-loaded iron oxide nanoparticles improved drug penetration in the skin, suggesting they may be promising for topical alopecia therapies.
10 citations
,
February 2015 in “Melanoma management” Dermoscopy is useful for many health professionals, not just dermatologists, in improving skin condition diagnoses and reducing unnecessary biopsies.
9 citations
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July 2022 in “Dermatology and Therapy” In this study, long-pulsed 755-nm alexandrite laser treatment for keratosis pilaris significantly improved skin roughness and redness, as well as follicular plug reduction, with good safety and patient satisfaction compared to a moisturizing lotion alone.
9 citations
,
October 2018 in “Elsevier eBooks” This article discusses how challenges in drug development and success rates are driving a shift in the pharmaceutical industry towards engineering targeted drug delivery systems, with nanomaterials offering potential solutions for selective therapeutic delivery.
7 citations
,
July 2019 in “International Journal of Molecular Sciences” This study found that PGA-4HGF nanoparticles enhanced hair growth in mice more effectively than 4HGF alone by increasing anagen phase duration and dermal papilla cell proliferation.
6 citations
,
April 2025 in “Communications Biology” In this study, researchers used a murine model of irritant contact dermatitis to reveal that hair follicle regions serve as key sites for neutrophil transepidermal migration, which requires MMP-9 expression stimulated by dermal monocytes.
5 citations
,
March 2025 in “World Journal of Urology” This study concluded that while remote interventions using digital health technology can enhance health-related outcomes, medication adherence, and economic status in kidney transplant recipients, their effect on tacrolimus concentration is not clearly understood.
3 citations
,
October 2021 in “Research Square (Research Square)” This study used in vivo confocal microscopy and a ResNet34 deep learning model to classify meibomian gland images with an AUROC greater than 0.95, indicating its potential for automatic diagnosis and screening of meibomian gland dysfunction.
1 citations
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February 2024 in “npj digital medicine” This study developed a deep-learning model using unannotated dermatology images from online forums, achieving 49.64% accuracy in classifying 22 skin diseases and 61.76% accuracy in detecting monkeypox, highlighting the potential of these images for skin disease diagnostics in China.
January 2024 in “Regenerative Biomaterials” This review introduces the potential of metal-organic framework-based functional composite materials in tissue engineering but reports no new results, emphasizing the need for further innovation in the field.
March 2015 in “Polish Journal of Public Health” This study found that capillaroscopic patterns varied among patients with systemic scleroderma, psoriasis, psoriatic arthritis, and alopecia, suggesting potential microcirculation disturbances; however, no correlations were observed with serum angiogenic markers.
March 2026 in “DergiPark (Istanbul University)” In this study, BTP-loaded solid lipid nanoparticles were developed and shown to protect hair from heat-induced damage by enhancing cuticle integrity and thermal resistance in simulated thermal straightening conditions.
In this study involving 13 patients with vitiligo-associated leukotrichia, minimal hair repigmentation was observed following treatment with fractional CO₂ laser and topical betamethasone, though the method was well tolerated, highlighting the need for further research to optimize treatment parameters.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a novel mechanism by which dsRNA-induced TLR3 activation and retinoic acid pathways contribute to new hair follicle formation after deep wounds in mice and suggested a similar potential in humans.
1 citations
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April 2026 in “Aesthetic Plastic Surgery” This study found that radiofrequency microneedling is effective and well-tolerated for improving various skin conditions, showing comparable efficacy to fractional lasers for atrophic acne scars with generally favorable patient satisfaction and safety.
38 citations
,
July 2019 in “Nature Communications” This study found that Par3 plays a crucial role in maintaining epidermal homeostasis by regulating Rho/actomyosin contractility and ensuring mitotic accuracy, with potential implications for other self-renewing epithelia.