37 citations
,
November 2003 in “Veterinary pathology” This study showed that in C3H/HeJ mice, focal follicular inflammation starts before overt hair loss, with inflammation severity possibly reaching a threshold causing hair follicle dystrophy prior to visible hair loss.
32 citations
,
January 2010 in “Journal of Korean Medical Science” This case report describes a rare instance of functioning adrenocortical oncocytoma in a 14-year-old girl with virilization and reviews related literature.
30 citations
,
July 2000 in “PubMed” This study used advanced analytical techniques to reveal that proteins and lipids are distributed unevenly in hair, with distinct structural differences depending on their location within the fiber.
28 citations
,
October 1985 in “The Journal of Cell Biology” This study identified two types of hard alpha-keratin filament assemblies in developing human hair follicles, which may help investigate the structural framework of mammalian keratin appendages.
26 citations
,
December 2022 in “Future Journal of Pharmaceutical Sciences” This review discusses the use of terpenes and invasomes as permeation enhancers for transdermal drug delivery, focusing on their potential applications in pharmaceutical formulations, but it reports no new experimental results.
26 citations
,
January 2022 The skin is essential for protection, temperature control, and immune defense.
26 citations
,
March 1995 in “Differentiation” This study isolated and sequenced the complete gene rKAP4L1, which encodes a cysteine-rich hair keratin-associated protein in rabbit hair follicles.
25 citations
,
May 1994 in “Journal of Investigative Dermatology” This study identified a novel gene, hacl-1, that is specifically expressed in the hair follicles of ICR mouse skin and is associated with their active state.
24 citations
,
October 2010 in “Tissue Engineering Part A” This study found that tissue-engineered skin using mouse fibroblasts successfully supported hair growth after grafting, but similar success was not observed using human fibroblast-derived tissue.
23 citations
,
May 2015 in “Science China Life Sciences” This article reviews how the microenvironment influences adult stem cell behavior and discusses strategies to enhance stem cell function but reports no new experimental results.
17 citations
,
May 2021 in “Journal of Applied Pharmaceutical Science” This review highlights that transferosomes, or ultradeformable lipids, show promise for improving dermal delivery, exhibiting efficient drug transport across the skin's barrier and offering potential benefits for treating chronic skin disorders with better bioavailability.
15 citations
,
April 2023 in “Biology” This review discusses the characteristics, extraction strategies, and potential applications of plant and algal lipid droplets but reports no new empirical findings.
11 citations
,
January 2016 in “Biointerphases” This study suggests that the outermost hair cuticle surface is rich in 18-methyleicosanic acid (18-MEA), supporting previous findings of its multilayer lipid and protein structure.
10 citations
,
April 2017 in “PLoS ONE” This study reports that the white rhinoceros has a unique integumentary structure among large herbivores, characterized by thick epidermis, organized collagen bundles, and the presence of coiled sweat glands.
9 citations
,
May 2008 in “Journal of Clinical Oncology” This article compiles references on toxic epidermal necrolysis and cutaneous reactions to anticancer agents but reports no new findings.
9 citations
,
November 2004 in “SKINmed Dermatology for the Clinician” This case report describes a 54-year-old man diagnosed with fibrosing alopecia in a pattern distribution, presenting with follicular inflammatory lesions and scleroatrophy on the scalp.
8 citations
,
July 2004 in “Journal of morphology” This study explored the structure and keratin composition of marsupial hairs, finding similarities in keratin localization to hairs in placental mammals, and highlighting potential roles of trichohyalin and transglutaminase during hair development and shedding.
8 citations
,
January 1984 in “Veterinary Pathology” This study found no conclusive link between prolonged mibolerone treatment and perifollicular mineralization in toy poodles, suggesting it may instead be a senile change common in the breed.
7 citations
,
January 2025 in “Frontiers in Microbiology” In this study, researchers investigated the immunohistopathological characteristics of the skin in individuals during the acute phase of chikungunya infection, revealing CHIKV antigens and inflammatory infiltrates in various skin components and highlighting the role of cytokines/chemokines in the disease's skin manifestations.
7 citations
,
November 2007 in “Annales de Dermatologie et de Vénéréologie” A man was diagnosed with a rare form of lupus after showing unique skin symptoms that responded well to treatment.
7 citations
,
March 1986 in “British Veterinary Journal” Canine skin has two main layers: the epidermis and dermis, with a supportive subcutis layer.
6 citations
,
September 2018 in “ACS applied bio materials” This study provides conclusive evidence of exogenous calcium fatty acid deposits forming between the cuticle layers in hair, affecting its optical and mechanical properties.
6 citations
,
September 2015 in “Journal of Medicinal Chemistry” This study synthesized and verified the structures of Setipiprant's major and minor metabolites, confirming their regio- and enantioselectivity from earlier proposals in a clinical study.
5 citations
,
July 2023 in “Microorganisms” This study analyzed skin biopsies from human monkeypox virus (hMPXV1) cases and found characteristic pustular stage features, including epidermal necrosis, shadow cell appearance, ballooned keratinocytes, and a dense inflammatory infiltrate, expanding histological knowledge crucial for understanding this disease and related Orthopoxvirus infections.
5 citations
,
January 1990 in “Journal of Society of Cosmetic Chemists of Japan” This study found that permanent wave lotion I extracts proteins from human hair, with molecular weights ranging from 5,000 to 65,000, which may elucidate hair damage mechanisms.
5 citations
,
January 1981 This article reviews the classification and complexity of keratin protein groups in hair follicles, but reports no new experimental results on their transcriptional events.
2 citations
,
March 2021 in “CRC Press eBooks” This review discusses the composition and benefits of shampoos including cleansing and conditioning properties, but reports no new research findings.
2 citations
,
September 2020 in “Pakistan Journal of Zoology” This study observed that red sindhi cattle have variations in skin structure between age and sex groups, with more developed skin appendages in adults and a higher density of sweat glands in younger cattle.
2 citations
,
June 2010 in “Medicina de Familia SEMERGEN” The girl's "dandruff" was actually harmless hair casts, not a hygiene issue.
2 citations
,
October 2007 in “Kafrelsheikh Veterinary Medical Journal” This study examined the morphological features of buffalo lips, finding that their structure includes distinct layers of skin, muscle, connective tissue, and glands.