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This study used molecular docking to identify stiripentol as a potential new inhibitor of the SRD5A2 enzyme, which is targeted for treating androgen-related diseases; however, in vivo trials are needed to validate its efficacy.

This review discusses the potential of solid-state fermentation for extracting polyphenolic compounds from agro-industrial wastes, but it reports no new experimental results.

This study observed that in a mouse model of androgenetic alopecia, treatments with LTF, 5% minoxidil, and LTF-DPC-EXO significantly promoted hair regeneration compared to the model group, potentially through modulation of the PI3K/AKT signaling pathway.

This review examines the phytochemistry, biological activities, and potential applications of Akebia species in medicine and cosmetology, highlighting the differences in chemical composition between A. quinata and A. trifoliata.

In this study, Astragaloside IV was found to inhibit apoptosis-related pathways in hair follicles of mice, suggesting it may serve as an alternative therapy for hair loss.

This study found that some synthesized heterocyclic derivatives showed promising 5α-reductase inhibitor, antiviral, and anti-tumor activities, surpassing several reference drugs in effectiveness.

This study found that procyanidin oligomers from apples and barley may stimulate hair growth by promoting hair epithelial cell proliferation and protecting them from apoptosis via MEK activation in a murine model.

This letter discusses the potential of green tea extract as a treatment for hirsutism but reports no clinical outcomes.

BrdU speeds up hair follicle aging and reduces hair quality.

This review summarizes causes and treatments of androgenetic alopecia with a focus on herbs as potential alternatives, but reports no new results and suggests more research is needed to validate these options.

This review outlines recent advancements in droplet-based microfluidic technology using food-grade emulsions to create diverse delivery systems by controlling droplet size, shape, and dispersity, while also discussing challenges in scaling these processes from laboratory to industrial applications.

This study found that aliphatic ester moieties in 16-formyl-17-methoxy dehydroepiandrosterone derivatives increased their potency as 5α-reductase type 2 inhibitors in vitro compared to finasteride.

This review describes deep eutectic solvents as a green alternative to toxic solvents in extracting bioactive compounds, highlighting their sustainability, production from natural ingredients, and beneficial properties for pharmaceutical applications.

This study found that compounds 21–23 and 25 exhibited strong 5α-reductase II inhibition in vitro and significantly reduced rat prostate weight, performing comparably to finasteride.

In this study, red rice was found to contain 87.2% carbohydrates, 9.1% proteins, and demonstrated bioactive properties due to its flavan-3-ol phenolic compounds, suggesting potential health benefits beyond its nutritional content.

This study analyzed the nutritional composition of 75 nutricosmetic products, finding common ingredients like biotin and zinc, but emphasized the need for further research on their effectiveness for hair and nail health.

This study observed that new trienone compounds consistently showed higher 5alpha-reductase inhibitory activity compared to corresponding dienones across various biological models.

This study introduced a new spectrofluorometric method using a synthesized organic fluorophore to effectively analyze darolutamide and thalidomide in pharmaceutical preparations and biofluids.

This study identified the major component of katuk leaf water extract as an alkaloid compound with a molecular mass of 406.3131 m/z, named (S, S)-5,5′-amino-4,4′-dihexyl-propyldihydropyrazol-3,3′-one.

This review explores the therapeutic potential of brown adipose tissue for treating polycystic ovary syndrome and reports no new experimental results, emphasizing the need for future research to develop effective strategies.

This review discusses the use of mushrooms and their bioactive compounds in cosmeceuticals and nutricosmetics and reports no new clinical findings, highlighting potential areas for future research and development.

This review presents current evidence on medicinal plants and their phytoconstituents, such as phenolic compounds, used in acne treatment, highlighting their potential as alternatives to conventional therapies due to issues like antibiotic resistance and high cost.

This review highlights recent advancements in using niosomes as nanocarriers for improved delivery and sustained release of active cosmetic compounds, discussing their properties, applications, and future potential in cosmetic chemistry.

In this study, 4-(4-(phenylaminocarbonyl)benzoyl) benzoic acid exhibited the strongest inhibitory activity against the human type 2 steroid 5α-reductase isozyme among the compounds tested.

This review highlights the potential of valorizing vegetable waste by extracting valuable biomolecules for use in food, nutraceuticals, and energy, noting that while promising methods exist, several niche areas lack sufficient research on a global scale.

This review evaluates the potential of natural products from marine microorganisms for cosmetic applications and reports no new experimental results, highlighting challenges and prospects in their use.

This study highlights the potential of chitosan nanoparticles to improve cannabidiol solubility and delivery for treating alopecia, suggesting a promising approach for transdermal delivery of hydrophobic compounds.

This study found that Ficus benghalensis leaf extracts reduced the activity of 5 α-reductase II and promoted hair growth in rabbits by elongating the hair follicle's anagen phase, suggesting potential for treating hair loss.

This narrative review reported that a variety of lifestyle-based interventions, such as specific dietary changes and physical activity, along with adjunctive therapies, have potential benefits in managing metabolic and hormonal outcomes in women with PCOS, although the variable study quality suggests further research is needed.

This review highlights that exosome-like nanovesicles derived from traditional Chinese medicinal herbs show potential in enhancing wound healing processes such as inflammation resolution and angiogenesis, suggesting promising applications in skin regeneration and therapeutic development.