January 2024 in “Wiadomości Lekarskie” This study highlights the role of innate immunity and purinergic signaling in regulating hematopoiesis and hematopoietic stem/progenitor cell specification. The researchers observed that these ancient pathways operate both paracrinally and autocrinally within HSPCs, maintaining their developmental function throughout evolution.
This study characterized the physical-chemical properties of Eclipta alba and identified compounds in the plant that could support its use in developing hair loss treatments.
This study observed that long-term laser hair removal in women may alter hair follicle structures and stem cell interactions, with dermal fibrosis potentially influencing hair regrowth prevention.
59 citations
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September 2021 in “Journal of Allergy and Clinical Immunology” This study found IL-17/IL-36 signaling to be predominant in both endotypes of Netherton syndrome, with distinct molecular profiles between NS-ILC and NS-SE lesions, offering potential therapeutic targets.
52 citations
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September 2021 in “Kidney International” In this report, a 23-year-old woman developed nephrotic syndrome and was diagnosed with lupus nephritis after receiving the first dose of the AstraZeneca COVID-19 vaccine, but causation is not established.
4 citations
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July 2017 in “Journal of Medical Case Reports” This case report highlights a rare presentation of acute lupus hemophagocytic syndrome with initially negative antinuclear antibodies, underscoring the higher sensitivity of the 2012 Systemic Lupus International Collaborating Clinics criteria for diagnosis.
April 2026 in “SHILAP Revista de lepidopterología” This case report illustrates that prompt diagnosis and treatment of myositis in an SLE patient can lead to symptom resolution and highlights this condition as a rare SLE complication.
35 citations
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July 1977 in “PubMed” This case report describes a woman with systemic lupus erythematosus who developed both pneumonitis and nephritis, with identical immune complexes found in her lungs and kidneys, suggesting a common pathogenetic mechanism.
4 citations
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June 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” This case report describes a 30-year-old woman diagnosed with both Rhupus and Rowell syndromes, and details her presentation and treatment plan, without reporting specific treatment outcomes.
October 2023 in “Journal of Integrative Medicine and Research” This case report describes a patient with lupus nephritis coexisting with discoid lupus erythematosus and vitiligo, noting improvement in proteinuria and DLE lesions following treatment, while vitiligo lesions persisted.
August 2025 in “Annals of the Rheumatic Diseases” This study observed that the relationships between various criteria used to classify systemic lupus erythematosus are more consistent with chance than predictable patterns, although connections within the same organ domain are relevant.
June 2023 in “Pharmaceuticals” This review reports that sex-related differences in pharmacological response have been observed in SARS-CoV-2 infection, dyslipidemia, and diabetes mellitus, with implications for treatment strategies; for example, men may respond better to genomic vaccines for SARS-CoV-2, while women may benefit more from certain antiviral medications.
September 2023 in “Russian Journal of Skin and Venereal Diseases” This study reported a rare case of necrobiosis lipoidica occurring on the scalp, leading to scarring alopecia, and highlighted a positive response to glucocorticoid therapy by reducing the brightness and growth of plaques over one month.
16 citations
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July 2012 in “The New England Journal of Medicine” This case report describes a 27-year-old man hospitalized with fatigue, myalgias, weakness, profound weight loss, and abnormal liver function, leading to a diagnosis after chest imaging revealed pneumomediastinum.
9 citations
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January 2020 in “Rheumatology Advances in Practice” In this study, SLE was found to be uncommon among patients with rheumatological complaints in Uganda, with a notable overlap with rheumatoid arthritis and frequent presentation of complications.
7 citations
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November 1977 in “JAMA” This case report describes group A streptococcal septicemia with monoarticular arthritis linked to an infected IUD, likely transmitted through sexual foreplay in a 28-year-old woman.
3 citations
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July 2021 in “Cutis” This case report described a 62-year-old woman with dermatomyositis whose multiple subcutaneous nodules persisted despite treatment with prednisone and methotrexate, prompting further dermatological evaluation.
August 2025 in “Scientific Reports” This study found that the protein C4BPA may link insulin resistance and acne vulgaris by influencing lipid metabolism and inflammatory pathways, suggesting it as a potential mediator in the pathogenesis of both conditions.
April 2024 in “Rheumatology” This case report describes a 22-year-old woman whose initial manifestation of systemic lupus erythematosus was vision-threatening vaso-occlusive retinopathy, highlighting the need for early identification and multidisciplinary treatment.
December 2023 in “Curēus” In this case study, a 36-year-old female with severe lupus enteritis and intestinal pseudo-obstruction showed significant clinical improvement after treatment with intravenous methylprednisolone, hydroxychloroquine, and cyclophosphamide, highlighting the complexities and challenges in diagnosing and managing atypical lupus manifestations.
126 citations
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April 2006 in “International Journal of Dermatology” This study found that frontal fibrosing alopecia and lichen planopilaris have similar histopathological features, but FFA exhibits more prominent apoptosis and less inflammation with spared interfollicular epidermis.
In this clinical case study, a 30-year-old man with systemic lupus erythematosus was diagnosed with both catastrophic antiphospholipid syndrome and acquired haemophilia A, successfully treated with immunosuppressive therapy, plasma exchange, and IVIG, leading to a favourable outcome.
In this study involving 30 Kazakh women with systemic lupus erythematosus, the researchers found a strong correlation between disease activity (SELENA-SLEDAI scores) and organ damage (SLICC/ACR scores), which depended on disease duration and reliably reflected cumulative disease activity.
This case report highlights that Tjalma Syndrome may present as a main symptom of systemic lupus erythematosus and should be considered in patients with ascites, pleural effusions, and elevated CA-125 levels.
December 1986 in “Plastic and Reconstructive Surgery” This study found that injected wax did not prevent androgenic alopecia and led to remodeling of the skull's outer cortex over a 30-year follow-up, necessitating removal due to a fibroxanthoma.
149 citations
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July 2002 in “Dermatologic clinics” This review discusses the pathogenesis, clinical presentation, diagnosis, and treatment of cutaneous lupus erythematosus, reporting no new clinical findings.
51 citations
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October 1981 in “British Journal of Dermatology” This study found that in patients who underwent jejuno-ileal bypass for morbid obesity, dapsone was effective in treating inflammatory skin lesions and joint symptoms when other antibiotics failed.
18 citations
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March 1985 in “Journal of The American Academy of Dermatology” Cocaine use can cause a blistering skin disease.
12 citations
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March 2004 in “International Journal of Dermatology” This case report describes a 16-year-old girl initially diagnosed with chronic telogen effluvium, later reassessed with Ludwig Stage 1 androgenetic alopecia, for which she began spironolactone treatment.
5 citations
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June 2018 in “Records of Natural Products” This study found that Lepidium sativum leaf extract significantly downregulated VEGF, TNF-α, and SRD5A2 gene expressions in HaCaT cells, suggesting potential benefits for inflammatory and androgen-dependent skin disorders.