The Complex Connection Between Vitiligo and Lupus: Exploring the Link

    Debashis Maikap, Phanidhar Dhanekula
    TLDR Vitiligo and lupus can occur together, requiring careful treatment to manage both conditions.
    A 37-year-old female presented with symptoms of vitiligo and discoid lupus erythematosus (DLE), including reddish raised lesions, severe hair loss, and pale-to-white lesions on her face and lips. Laboratory tests revealed elevated dsDNA levels and low serum complement levels, leading to a diagnosis of lupus nephritis coexisting with DLE and vitiligo. Treatment with prednisolone, mycophenolate mofetil, and hydroxychloroquine improved her proteinuria and DLE lesions, but the vitiligo lesions persisted. The study highlights the rare coexistence of DLE and vitiligo and discusses treatment options, emphasizing caution with phototherapy due to potential exacerbation of DLE lesions.
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