130 citations,
January 1994 in “Differentiation” Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.
113 citations,
November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
110 citations,
July 2017 in “Immunology” Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
72 citations,
November 2012 in “PloS one” The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
61 citations,
June 2014 in “Scientific Reports” Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
58 citations,
January 2020 in “International Journal of Molecular Sciences” Different methods of preparing Platelet-Rich Plasma (PRP) can affect wound healing and hair regrowth in plastic surgery. Using a kit with specific standards helps isolate PRP that meets quality criteria. Non-Activated PRP and Activated PRP have varying effects depending on the tissue and condition treated. For hair regrowth, Non-Activated PRP increased hair density more than Activated PRP. Both treatments improved various aspects of scalp health.
56 citations,
September 2013 in “Experimental Dermatology” The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.
56 citations,
February 2010 in “PLOS ONE” Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
54 citations,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.
53 citations,
April 2018 in “Journal of The American Academy of Dermatology” Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.
52 citations,
May 2015 in “PLOS Genetics” miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.
42 citations,
October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
41 citations,
November 2011 in “The Journal of Dermatology” Some hair loss disorders are caused by genetic mutations affecting hair growth.
40 citations,
January 2009 in “Skin Pharmacology and Physiology” Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.
30 citations,
June 2021 in “British Journal of Dermatology” Mutations in the WNT10A gene can cause skin, hair, teeth, and other disorders, and may also affect other areas like kidney and cancer, with potential for targeted treatments.
24 citations,
January 2020 in “International Journal of Molecular Sciences” Some plants with flavonoids may help treat hair loss and promote hair growth.
23 citations,
February 2020 in “PLOS genetics” Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.
21 citations,
June 2016 in “Genesis” Researchers identified specific genes that are important for mouse skin cell development and healing.
19 citations,
January 2015 in “Scientific Reports” GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.
19 citations,
June 2002 in “American Journal of Dermatopathology” Apoptosis contributes to hair loss in androgenetic alopecia.
15 citations,
May 2017 in “Lasers in Medical Science” Low-level laser treatment helps mice grow hair by increasing certain protein levels linked to hair growth.
14 citations,
October 2018 in “PloS one” Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
11 citations,
June 2017 in “Journal of cell science” AGD1's PH domain is essential for its role in root hair growth and polarity.
11 citations,
October 2001 in “Tissue engineering” Cultured epithelium can form hair follicles when combined with dermal papillae.
7 citations,
August 2017 in “PloS one” Key genes linked to hair growth and cancer were identified in hairless mice.
6 citations,
February 2022 in “The journal of neuroscience/The Journal of neuroscience” Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
5 citations,
January 2022 in “PloS one” Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.
2 citations,
September 2023 in “PLoS biology” Newly divided skin cells quickly move to join skin structures due to tissue tension and specific signals.
1 citations,
January 2015 in “Journal of nutrition & health” Fish oil improves skin health in people with diabetes and high cholesterol.
June 2024 in “Research Square (Research Square)” Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.