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Skin fat plays a key role in immune defense and healing beyond just storing energy.

Activating Notch signaling can kill basal cell carcinoma cells.

Plasma-activated liquid can kill harmful cells, speed up wound healing, and potentially treat cancer without damaging healthy cells.

Curcumin can be effectively loaded into polystyrene nanoparticles, which are safe for human cells and more biocompatible with curcumin inside.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.

Some hair protein genes evolved early and were adapted for use in hair follicles.

Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.

B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.

Corin helps control salt and sweat release in sweat glands.

Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.

The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Ayurvedic remedies may boost immunity and balance in cancer treatment but need more research.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

LEF1 is essential for the development of airway glands and is regulated by the Wnt/ß-catenin pathway.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.