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High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.

Proper skin toxicity management in chemotherapy is key to continuing treatment and keeping patient quality of life high.

Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.

PDCD4 is important for controlling skin cell growth and healing.

A substance called sodium zinc dihydrolipoylhistidinate can significantly reduce hair loss caused by chemotherapy in rats.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Antihelminthic drugs treat worm infections but face challenges like low treatment coverage and potential drug resistance, with various side effects reported for different drugs.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Lactate production is important for activating hair growth stem cells.

Some medicinal plants can help heal wounds and may lead to new treatments.

Stem cell niches support, regulate, and coordinate stem cell functions.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.