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research Heterozygous COL5A1 Deletion in a Cat with Classical Ehlers-Danlos Syndrome
A cat's poor wound healing was linked to a genetic deletion in the COL5A1 gene.
research Tsc2 Disruption in Mesenchymal Progenitors Regulates Hair Follicles and TGF Beta Signaling
Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.
research Combined Deletion of the Vitamin D Receptor and Calcium-Sensing Receptor Delays Wound Re-Epithelialization
Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.
research Transgenic Mice Overexpressing CD109 in the Epidermis Display Decreased Inflammation and Granulation Tissue and Improved Collagen Architecture During Wound Healing
Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.
research Clinical Case Notes: Retinoblastoma, Microphthalmia, and Chromosome 13q Deletion Syndrome
The document concludes that careful diagnosis is crucial for chromosome 13q deletion syndrome, tamoxifen can cause reversible eye damage, finasteride may be linked to cataracts, and OCT is useful for diagnosing macular diseases.
research Filamin A Mediates Wound Closure by Promoting Elastic Deformation and Maintenance of Tension in the Collagen Matrix
Testosterone may worsen hair loss by affecting hair growth signals, while different prostaglandins can either hinder or promote hair growth.
research Effect of Ginsenoside Rd on Dermal-Epidermal Junction in Fibroblast
Ginsenoside Rd may help improve skin aging by increasing collagen in the skin.
research Identification of Fetuin A as a Potential Modulator of Scar Formation
Fetuin A may increase collagen production and promote scarring.
research Clinical Case Notes: Tamoxifen Optic Neuropathy
A boy with chromosome 13q deletion syndrome developed eye cancer, a woman with breast cancer lost vision due to a rare side-effect of her treatment, a man's vision worsened after using a hair loss drug, and two rare disorders were discussed. Optical Coherence Tomography is useful for diagnosing and monitoring these conditions.
research Clinical Case Notes: Lipoid Proteinosis - A Rare Disorder with Pathognomonic Lid Lesions
A baby boy with 13q deletion syndrome had eye cancer, a woman's vision improved after stopping a breast cancer drug, a man developed cataracts from using Propecia, and a rare skin disorder called Lipoid Proteinosis was discussed. Also, a tool called OCT is useful for diagnosing macular diseases.
research Read-Through for Nonsense Mutations in Type XVII Collagen-Deficient Junctional Epidermolysis Bullosa
A new therapy for a skin blistering condition has not been developed yet.
research Expression of Nidogen1 in Basal Cell Carcinoma
Higher levels of nidogen1 and type IV collagen are found in basal cell carcinoma compared to normal skin.
research Author Response: Type XVII Collagen Coordinates Proliferation in the Interfollicular Epidermis
Type XVII collagen helps control skin cell growth and may have anti-aging effects.
research Decision Letter: Type XVII Collagen Coordinates Proliferation In The Interfollicular Epidermis
Type XVII collagen may help prevent skin aging.
research Clinical Case Notes: Intraorbital Ophthalmic Artery Aneurysms
Eye exams are crucial for kids with 13q deletion syndrome, tamoxifen can cause vision loss, Propecia may lead to cataracts, Lipoid Proteinosis causes skin bumps, and OCT is useful for diagnosing macular diseases.
research Hair Follicle Stem Cells: A New Arena
Hair follicle stem cells have significant potential for treating various disorders.
research Cardiac Outflow Tract Septation Defects in a DiGeorge Syndrome Model Respond to Minoxidil Treatment
Minoxidil treatment improves heart defects in a DiGeorge syndrome model.
research Dual Growth Factor Releasing Multi-Functional Nanofibers for Wound Healing
The nanofibers with two growth factors improved wound healing by supporting structure, preventing infection, and aiding tissue growth.
research Mechanical Forces in Skin Disorders
Skin problems can be caused or worsened by physical forces and pressure on the skin.
research Fibromodulin Reduces Scar Formation in Adult Cutaneous Wounds by Eliciting a Fetal-Like Phenotype
Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.
research Fibromodulin Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors During Adult Mouse Skin Wound Healing
Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
research Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging
Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
research Rice Bran Mineral Extract Increases the Expression of Anagen-Related Molecules in Human Dermal Papilla Through Wnt/Catenin Pathway
Rice bran mineral extract may help promote hair growth and prevent hair loss.
research Anti-Aging Effects of Retinoid Hydroxypinacolone Retinoate on Skin Models
Hydroxypinacolone retinoate is a potent anti-aging ingredient for skin that is more effective and less irritating than other forms of retinoids.
research Efficacy of Subcutaneous Injection of Platelet-Rich Plasma in Alopecia: A Clinical and Histological Pilot Study on a Rat Model with a Six-Month Long-Term Follow-Up Experience
Injecting platelet-rich plasma under the skin significantly improves hair growth and quality without harmful effects.
research Minoxidil Cannot Be Used To Target Lysyl Hydroxylases During Postnatal Mouse Lung Development: A Cautionary Note
Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Cellutome Epidermal Harvesting System and In Vivo Reflectance Confocal Microscopy as a Novel Wound Healing Assessment Protocol
The new protocol using Cellutome™ and RCM safely assesses wound healing in detail.
research Tensor Effect of Anigozanthos Flavidus Flower Extract: Modulation of Tenascin-X to Regenerate the Skin
Anigozanthos Flavidus flower extract helps regenerate skin and reduce wrinkles.