This study focused on developing a nanoemulsion-based gel for delivering minoxidil, aiming to enhance its contact time with the scalp and potentially improve skin absorption compared to conventional topical solutions.
August 2024 in “Indian Journal of Animal Research” In this study, dermatophytosis in cattle around Parbhani was found to have a prevalence of 17.2%, with Clove oil treatment showing the quickest recovery in 7 days.
In this study, clove leaf ethanol extract shampoo at 15% concentration effectively promoted hair growth in male white rats, though it was less effective than 5% minoxidil.
August 2024 in “Panggung Kebaikan” In this community service project, the researchers found that educating the public about using clove leaves as a herbal remedy for hair growth issues in Indonesia significantly increased public knowledge from 17.91% to 45.86%.
February 2024 in “International journal of biology, pharmacy and allied sciences” This review discusses the potential of plant-based preparations for treating hair loss and reports no new clinical results; the authors highlight herbs with evidence of efficacy against alopecia.
December 2023 in “Azerbaijan Pharmaceutical and Pharmacotherapy J” This study formulated a minoxidil-loaded submicron emulsion-based topical gel, which demonstrated effective in vitro release, ex vivo permeation, and stability, suggesting it may offer a targeted treatment approach for alopecia compared to traditional methods.
November 2023 in “Scholars journal of applied medical sciences” This study conducted in Rabat surveyed 100 individuals with afro-textured hair to identify plant-based treatments, finding twelve plant species purportedly effective in managing hair issues, with Ricinus communis, Cocos nucifera, and Aloe barbadensis being the most frequently cited.
August 2023 in “Health Sciences and Pharmacy Journal” In this review, researchers identified 10 natural plants, including candlenut and clove, that have shown potential to inhibit alopecia progression and stimulate hair growth due to their diverse phytochemical and pharmacological properties in vitro and in vivo.
January 2023 in “International Journal of Research Publication and Reviews” This review details the causes, symptoms, and treatments for dandruff, emphasizing herbal ingredients with anti-dandruff properties used in shampoos and exploring their antifungal and anti-inflammatory mechanisms. It highlights dandruff's exploitation by personal care companies due to the lack of medical interventions.
3 citations
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February 2024 in “International Journal of Pharmaceutical Sciences Review and Research” This study suggests that a herbal oil formulation combining various plant and oil ingredients may effectively promote healthy hair growth and address concerns like baldness, dryness, and dandruff, supported by favorable evaluations of its physical and chemical properties.
50 citations
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June 1993 in “European journal of biochemistry” This article reviews the regulation of gene expression and assembly of intermediate filaments but presents no new findings.
19 citations
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July 1994 in “Journal of Dermatological Science” This study identified and characterized human hair-specific keratin genes, revealing their sequence homology with mouse counterparts and expression in hair follicle precortical cells.
10 citations
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January 2016 in “Planta Medica” This study found that topical formononetin treatment promoted hair regrowth in mice by normalizing hair follicle size and inhibiting apoptosis-related pathways.
7 citations
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May 2013 in “PubMed” In this randomized, placebo-controlled study, the tested cosmetic ingredient containing Trifolium pratense flower extract and a biomimetic peptide increased anagen hair and improved the anagen/telogen ratio over four months in individuals with recessing hair.
1 citations
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January 2020 in “Archives of Medical Research” Formononetin, found in red clover, may treat hair loss with fewer side effects.
January 2015 in “Hair therapy & transplantation” This review discusses natural and botanical products examined for treating alopecia and reports no clinical results; the authors note growing research interest in these treatments.
January 2008 in “Durham e-Theses (Durham University)” This study observed that stem cells from the hair follicle dermis share similarities with bone marrow-derived mesenchymal stem cells and have potential to form neural-like cells under specific conditions.
January 1992 in “Juntendo Medical Journal” This article discusses male pattern baldness and the potential of androgen inhibitors, reporting on previous findings and the need for new preventive measures; it does not present new clinical results.
3 citations
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January 2023 in “Skin appendage disorders” This study reported five cases of alopecia areata following COVID-19 vaccination, with one patient experiencing worsening symptoms with each vaccine booster.
1 citations
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April 2018 in “Journal of Investigative Dermatology” This open-label study found that oral tofacitinib led to significant hair regrowth in patients with moderate-to-severe alopecia areata, supported by changes in gene expression and T cell dynamics.
In this study, researchers discovered that the HrasG12V oncogenic mutation in murine skin epithelial cells initially promotes progenitor cell renewal but later leads to a balanced differentiation, stabilizing clone growth.
May 2018 in “White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)” In this study, researchers found that alopecia areata patients show a significant reduction in suppressive regulatory T-cells and an increase in inflammatory T-cell populations, suggesting an immunological imbalance contributing to the disease.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
57 citations
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January 1987 in “Journal of Biological Chemistry” This study identified and sequenced several keratin cDNA clones showing distinct expression patterns in mouse epithelia, with in situ hybridization highlighting differences in keratin distribution between normal and hyperproliferative tissues.
9 citations
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July 2013 in “Experimental Dermatology” This study demonstrates that the ability of human hair follicle keratinocytes to form clones decreases with ageing.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that excessive consumption of nutmeg, ginger, cloves, and mixed spices led to significant liver damage and other health issues in laboratory mice.
July 2026 in “Journal of the Science of Food and Agriculture” This study found that adding sheep wool to soil can increase water retention and delay drought stress in red clover, although further research is needed to confirm these effects under field conditions.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, excessive consumption of nutmeg, ginger, cloves, and mixed spices caused significant liver damage and other harmful effects in mice, leading to severe health issues and mortality.
23 citations
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October 2008 in “Experimental and Clinical Endocrinology & Diabetes” This study found that measuring cortisol in human hair can reflect increased cortisol production for up to six months, with the highest concentration in hair closest to the scalp.
4 citations
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June 2025 in “Cell Reports” In this study using the C3H/HeJ mouse model of alopecia areata, researchers found that hyperexpanded CD8+ T cell clones were sufficient to initiate disease, establishing a causal link between T cell clonality and pathogenicity.