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White hirsute women with PCOS have higher insulin resistance, but similar nitric oxide and fibrinogen levels compared to those with idiopathic hirsutism.

Ustekinumab significantly improved sexual function and quality of life for people with moderate to severe psoriasis.

Methotrexate treatment for rheumatoid arthritis has a serious infection rate of about two per 100 patient-years.

Hair transplantation is beneficial if the right patients are chosen and the procedure is done carefully.

Lower nitric oxide and higher fibrinogen found in hirsute women; impaired sexual function in 22.6% of hair loss patients, linked to psoriasis severity.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Fibrinogen/LDL apheresis may improve speech perception in sudden hearing loss, especially for those with high fibrinogen and LDL levels.

Some medicinal plants can help heal wounds and may lead to new treatments.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.

Using platelet-rich plasma with microneedling works better for acne scars than microneedling with water.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

New nanocomposites with copper show promise for healing burn wounds and regenerating skin.

Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.