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December 1986 in “Cancer Chemotherapy and Pharmacology” Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.
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August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” The new "differential stripping" method effectively measures how much substance gets into hair follicles.
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January 2017 in “Development” Blood vessels and specific genes help turn cartilage into bone when bones heal.
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February 2004 in “Current anthropology” Humans lost body hair relatively recently in evolution.
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June 2002 in “Veterinary record/The veterinary record” Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.
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November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
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December 1991 in “Antimicrobial Agents and Chemotherapy” Dextran sulfate was found to be toxic and ineffective for treating HIV.
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December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
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June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
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January 1987 in “Journal of The American Academy of Dermatology” The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.
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April 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.
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May 2015 in “European journal of pharmaceutics and biopharmaceutics” The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.
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March 2012 in “Expert Opinion on Drug Delivery” Liposomes could improve how skin care products work but are costly and not very stable.
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December 2003 in “American Journal of Pathology” Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.
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April 2000 in “European Urology” Finasteride lowers risk of urinary issues and surgery by over 50% in 4 years.
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January 2016 in “Journal of The American Academy of Dermatology” Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.
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September 1995 in “Journal of The American Academy of Dermatology” Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.
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June 2008 in “The FASEB Journal” One minoxidil-sensitive potassium channel exists in human hair follicles.
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August 2020 in “Dermatologic therapy” COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.
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November 2017 in “Analytica Chimica Acta” Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.
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June 2017 in “Nature Communications” A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
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September 2014 in “Therapeutic Delivery” Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
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January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
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June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
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July 2008 in “Aaps Pharmscitech” Ethosomes improve finasteride delivery through skin for hair loss treatment.
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December 2001 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.
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August 2020 in “Cell” Muscles and nerves that cause goosebumps also help control hair growth.
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March 2017 in “Stem Cell Reports” SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.
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April 1999 in “Dermatologic Clinics” The document concludes that follicular unit transplantation offers more natural results and better graft survival than older hair transplant methods.
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April 2016 in “Science Advances” Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.