January 2023 in “Karger Kompass. Dermatologie” Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.
August 2022 in “IntechOpen eBooks” Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.
489 citations,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
142 citations,
March 2019 in “Molecules/Molecules online/Molecules annual” Cannabinoids may help treat various skin conditions.
39 citations,
May 2019 in “The journal of immunology/The Journal of immunology” Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.
37 citations,
December 2021 in “Cells” Alopecia areata severity and treatment response are linked to specific cytokine levels.
37 citations,
December 2014 in “JAMA dermatology” A woman with severe hair loss was successfully treated with the drug adalimumab.
31 citations,
August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
28 citations,
April 2023 in “Stem cell research & therapy” Tiny vesicles from stem cells could be a new treatment for healing wounds.
27 citations,
May 2019 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” The best method for urethral reconstruction is using hypoxia-preconditioned stem cells with autologous cells on a vascularized synthetic scaffold.
24 citations,
August 2021 in “Biologics” Stem cell therapy shows promise in improving burn wound healing.
22 citations,
August 2021 in “Frontiers in medicine” Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.
22 citations,
August 2020 in “Cells” TGM3 is important for skin and hair structure and may help diagnose cancer.
15 citations,
January 2015 in “Stem cells international” Human hair follicle stem cells can be turned into red blood cells.
11 citations,
July 2022 in “Journal of Materials Science: Materials in Medicine” A new hydrogel with stem cells from the human umbilical cord speeds up healing in diabetic wounds.
11 citations,
January 2022 in “Journal der Deutschen Dermatologischen Gesellschaft” Alopecia areata is a chronic condition causing hair loss, with new treatments targeting the immune system showing promise.
8 citations,
December 2022 in “Regenerative Therapy” New regenerative treatments for hair loss show promise but need more research for confirmation.
8 citations,
July 2022 in “Biomedicines” Autophagy helps keep skin healthy and may improve treatments for skin diseases.
8 citations,
January 2019 in “Turkish journal of medical sciences” Ischemic modified albumin could be a new indicator of oxidative stress in people with alopecia areata.
4 citations,
September 2021 in “Biomolecules” Using Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells together can improve healing, including wound healing, bone regeneration, and hair growth.
3 citations,
October 2023 in “Military Medical Research/Military medical research” Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
3 citations,
October 2021 in “Brain Sciences” Long-term use of Risperidone may be linked to a serious skin condition in bipolar patients, affecting their overall well-being.
3 citations,
April 2023 in “Frontiers in Pharmacology” ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.
2 citations,
January 2023 in “Pharmaceuticals” Sex and sex hormones can affect brain inflammation in Parkinson's disease, with male mice being more affected and female mice showing a protective effect.
2 citations,
July 2022 in “Cell Regeneration” Understanding hair growth involves complex factors, and more research is needed to improve treatments for hair loss conditions.
2 citations,
August 2019 in “Journal of skin and stem cell” The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.
2 citations,
April 2022 in “Genes” The study found that the hair loss condition in Cesky Fousek dogs is influenced by multiple genes affecting skin and muscle structure, fat metabolism, and immunity.
1 citations,
May 2023 in “European Journal of Human Genetics” Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.
April 2024 in “International journal of molecular sciences” Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.