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Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Prostaglandin D₂ might be targeted for new male pattern baldness treatments.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

Despite progress in treatment, the exact cause of Alopecia areata is still unknown.

Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Lupus can affect the scalp and nails, often causing hair loss and nail damage, and needs early aggressive treatment to prevent permanent damage.

Apremilast was not effective in treating moderate-to-severe alopecia areata.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

Quercetin may help with PCOS symptoms, but more research is needed.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.