March 2025 in “Pediatric Rheumatology” This study found that clinicians frequently prefer cyclophosphamide over rituximab for induction therapy of childhood-onset systemic lupus erythematosus and ANCA-associated vasculitis, following a high-dose regimen recommended by the NIH.
1 citations
,
November 2008 in “Gerontology” This article discusses the increasing use of lifestyle drugs by healthy individuals to alter appearance or slow aging and emphasizes the need for doctors to consider side effects and contraindications, but it reports no new clinical findings.
November 2020 in “Journal of Pharmaceutical Sciences” This study suggests a decision tree using in vitro metabolic clearance to identify early drug candidates likely to experience nonlinear pharmacokinetics due to intestinal CYP3A-related metabolism.
3 citations
,
May 2019 in “Australasian Journal of Dermatology” This letter to the editors discusses the nature of alopecia in Cronkhite–Canada syndrome and questions whether it is truly telogen effluvium, but it reports no new clinical findings.
February 2026 in “International Journal of Homoeopathic Sciences” In this case report at Dr Batra’s Homeopathy Clinic, individualized classical homeopathy over 54 months led to sustained hair regrowth and disease stabilization in a patient with chronic alopecia areata, illustrating the potential benefits of holistic treatment approaches in managing this condition.
26 citations
,
July 1992 in “International Journal of Dermatology” In this study, treating refractory alopecia universalis with low-dose cyclosporine A and prednisolone improved symptoms, with no recurring alopecia six months post-treatment and enhancements in immunologic function.
October 2005 in “The Journal of clinical investigation/The journal of clinical investigation” This review discusses various theories and mechanisms of aging, highlighting recent findings on the hormone Klotho, which increased lifespan in mice in laboratory settings, but notes a potential trade-off with human health risks.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The study discusses how stress can lead to telogen effluvium, a form of hair loss, by triggering hormonal imbalances and affecting microcirculation and hair follicle homeostasis. It highlights both medicinal and non-medicinal interventions, such as relaxation techniques and gentle care rituals, as potential treatment strategies.
1 citations
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November 2022 in “Journal of Investigative Dermatology” This study found that ALRN-6924, a clinical-stage dual inhibitor, can selectively protect human scalp hair follicles from paclitaxel-induced toxicity and damage by inducing transient cell cycle arrest in healthy cells without affecting cancer cells, potentially reducing chemotherapy-induced alopecia.
January 2025 in “Dermatology and Therapy” This review updates dermatologists on both FDA-approved and off-label hormonal therapies, including combined oral contraceptives, clascoterone, and spironolactone, used for acne treatment, providing insights into emerging approaches for managing the condition.
24 citations
,
December 2011 in “International Journal of Cancer” This study found that the collagen-binding fusion protein PTH-CBD significantly improved hair regrowth and follicle health in mice after chemotherapy, suggesting potential as a therapy for chemotherapy-induced alopecia.
1 citations
,
May 2016 in “The Veterinary Journal” This study found that intradermal reactivity to histamine in dogs varies with time of day, and glucocorticoids may influence this variation.
53 citations
,
July 1981 in “Journal of Endocrinology” In this study, α-MSH and cyclic AMP were found to stimulate melanogenesis in hair follicle cultures, while cyclic GMP and melatonin inhibited melanin production but not tyrosinase activity.
21 citations
,
January 2013 in “Annals of dermatology/Annals of Dermatology” In this study, combination therapy with cyclosporine and PUVA for severe alopecia areata resulted in a majority of patients showing only fair to poor responses, though some improvements were noted.
4 citations
,
January 2019 in “Clinical and Experimental Dermatology” This study reported improvements in trichotillomania symptoms among patients who engaged with a psychodermatology service, despite a high rate of missed appointments.
7 citations
,
December 2016 in “British Journal of Dermatology” This report presents evidence that alopecia areata incognita may be a possible mechanism of hair loss in patients with Cronkhite–Canada syndrome.
October 2020 in “Journal of the American Society of Nephrology” In this case study, drospirenone use masked the diagnosis of a rare form of congenital adrenal hyperplasia, suggesting a possible delay in detecting underlying endocrinopathies.
9 citations
,
February 2019 in “BMC cancer” This study found that M30 may protect against cyclophosphamide-induced alopecia in mice by enhancing hair growth and preventing abnormal hair, suggesting its potential as a treatment.
25 citations
,
October 2019 in “Journal of Endocrinological Investigation” This study reported that both drospirenone and chlormadinone acetate oral contraceptives had similar beneficial effects on clinical, metabolic, and hormonal parameters in women with polycystic ovary syndrome over six months.
This research reports that after genotoxic stress from ionizing radiation or chemotherapy, hair follicles can utilize progenitor cells from transit-amplifying compartments, not quiescent stem cells, for repair, suggesting a potential therapeutic approach to prevent therapy-induced hair loss by activating these progenitors.
22 citations
,
February 2002 in “Journal of theoretical biology” This study found that a stochastic follicular automaton model replicates hair follicle cycle fluctuations, with deterministic simulations aligning with steady-state levels as follicle numbers increase.
March 2026 in “Anti-Aging Eastern Europe” This review examines current evidence on personalized management strategies for PCOS, but does not present new clinical results; the authors advocate for treatments tailored to predominant symptoms and individual health profiles.
44 citations
,
June 2018 in “Journal of Visualized Experiments” This paper presents a culturally informed protocol designed to improve the collection of hair samples from African Americans for cortisol measurement, illustrating its application with community-based study data.
1 citations
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February 2023 in “Daehan ui'sa hyeobhoeji/Daehan uisa hyeopoeji” This article reviews strategies for managing the side effects of cytotoxic chemotherapy in primary healthcare settings and reports no new clinical findings.
Prescription and alternative therapies for hair loss will be compared for effectiveness.
April 2019 in “Biometrics” This discussion reviews a hybrid phase I-II/III clinical trial design that enables dose re-optimization in phase III, but reports no new findings.
December 2024 in “Chemical Senses” This study investigated Cronkhite-Canada syndrome in ten patients, finding severe taste abnormalities in the anterior tongue linked to tongue papillary atrophy, which improved with treatment. Taste function tests were helpful in evaluating treatment effectiveness for this rare disorder.
25 citations
,
June 2020 in “Dermatology practical & conceptual” This study reviewed treatments for chemotherapy-induced hair loss, finding that scalp cooling is FDA-approved for prevention, while minoxidil and bimatoprost may aid post-chemotherapy regrowth. The authors emphasized tailored therapies and the potential utility of tools like trichoscopy and trichogram.
May 2023 in “Journal of Cosmetic and Laser Therapy” This research observed that combination therapy targeting different pathogenetic pathways is more effective than monotherapy in treating female pattern hair loss, offering a more aggressive treatment approach that can include modalities such as minoxidil, spironolactone, and finasteride.
October 2014 in “Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)” This research discusses the time-of-day-dependent role of protein-complex assembly in the differentiation of human epidermal stem cells and highlights the context-dependent functioning of human protein complexes.