Treatment for Chemotherapy-Induced Alopecia in Mice Using Parathyroid Hormone Agonists and Antagonists Linked to a Collagen Binding Domain

    December 2011 in “ International Journal of Cancer ”
    Ranjitha Katikaneni, Tulasi Ponnapakkam, Hirofumi Suda … Robert Gensure
    Studysummary This study found that the collagen-binding fusion protein PTH-CBD significantly improved hair regrowth and follicle health in mice after chemotherapy, suggesting potential as a therapy for chemotherapy-induced alopecia.
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    Research cited in this study 8

    1. Prevention of Chemotherapy-Induced Alopecia in Rodent Models Cell stress & chaperones · 2008
    2. A Topical Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor Antagonist Stimulates Hair Growth in Mice Endocrinology · 2006
    3. Protection Against Chemotherapy-Induced Alopecia Pharmaceutical Research · 2006
    4. Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors Science · 2001
    5. Do Hair Bulb Melanocytes Undergo Apoptosis During Hair Follicle Regression (Catagen)? ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    6. Reduction of Intrafollicular Apoptosis in Chemotherapy-Induced Alopecia by Topical Calcitriol Analogs ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    7. Chemotherapy-Induced Alopecia in Mice: Induction by Cyclophosphamide, Inhibition by Cyclosporine A, and Modulation by Dexamethasone PubMed · 1994
    8. Drug-Induced Hair Loss and Hair Growth Drug Safety · 1994

    Related research 2

    1. Keratins of the Human Hair Follicle International review of cytology · 2005
    2. Trans-Species Hair Growth Induction by Human Hair Follicle Dermal Papillae Experimental Dermatology · 2001