24 citations
,
May 2006 in “Journal of Investigative Dermatology” This study found that allergen treatment in alopecia areata mice appeared to alter leukocyte subset distribution and impaired dendritic cell migration, which may affect T-cell activation and hair follicle recovery.
24 citations
,
June 1999 in “The Pediatric Infectious Disease Journal” In this case report, a 2-year-old boy initially diagnosed with Sweet syndrome was later found to have chronic granulomatous disease, highlighting the importance of considering CGD in unusual cases of Sweet syndrome.
23 citations
,
June 2017 in “Rejuvenation Research” In this study, minoxidil treatment in aged mice increased elastin expression and improved aortic structure and function, suggesting its potential for arterial remodeling in aging.
23 citations
,
September 1999 in “Archives of Dermatology” Chronic telogen effluvium is a common hair loss condition with specific characteristics and treatment options.
22 citations
,
April 2022 in “Stem cell research & therapy” This study found that extracellular vesicles derived from hair follicle mesenchymal stromal cells demonstrated similar potential to those from adipose tissue in promoting cell proliferation and migration, enhancing angiogenesis, and protecting cells under stress, suggesting promise for chronic wound treatment.
21 citations
,
April 2010 in “Molecular Medicine Reports” This review discusses zinc supplementation as a complementary therapy for chronic hepatitis C, noting its potential benefits in improving treatment outcomes and reducing side effects, but reports no new clinical results.
21 citations
,
February 1988 in “Toxicology” This study found that high doses of TCB caused severe toxicity in cotton top marmoset monkeys, with clinical and histological changes similar to those in humans and other primates exposed to PCBs.
20 citations
,
February 2004 in “Clinical & Experimental Immunology” This study suggests that long-term treatment with the contact sensitizer SADBE in mice may reduce leucocyte traffic in alopecia areata through impaired leucocyte extravasation.
19 citations
,
June 2015 in “Actas Dermo-Sifiliográficas” This review discusses various skin conditions linked with chronic kidney disease and highlights effective treatments but does not provide new clinical results.
19 citations
,
September 2004 in “PubMed” This review examines the psychological effects of chronic hair diseases, noting significant impacts on self-confidence and quality of life, particularly in women with androgenetic alopecia and patients undergoing chemotherapy.
18 citations
,
March 1974 in “Acta dermato-venereologica” Chronic kidney disease can cause skin and nail problems.
17 citations
,
July 2019 in “Lupus Science & Medicine” In this study, gene expression analysis of plucked hair follicles from scalp lesions was sufficient to differentiate chronic discoid lupus erythematosus from psoriasis and healthy controls, suggesting a non-invasive diagnostic potential.
17 citations
,
June 2019 in “Cellular signalling” Minoxidil treatment in mice preserved the integrity of elastic lamellae and improved arterial biomechanical properties, especially in females, suggesting it could be an anti-arterial aging agent potentially suitable for female-targeted therapies.
17 citations
,
June 2016 in “Croatian Medical Journal” In this study, vitiligo and alopecia areata were more common among patients with chronic graft-vs-host disease than previously reported, linked to higher NIH skin scores and greater immunosuppressive treatment.
17 citations
,
February 2012 in “Cutaneous and Ocular Toxicology” This study found that xerosis and pruritus are prevalent in patients with chronic renal failure undergoing hemodialysis, highlighting the importance of early recognition of skin issues to alleviate discomfort and reduce complications.
17 citations
,
January 1993 in “Dermatology” This report describes two cases of chronic arsenicism, one involving criminal poisoning by a sibling and the other associated with prolonged use of Fowler's solution.
16 citations
,
November 2024 in “Human Genetics and Genomics Advances” This study identified 24 independent genetic variations and 127 unique genes associated with nociplastic pain, suggesting it is a complex, heritable trait with links to various cognitive and metabolic pathways.
16 citations
,
January 2021 in “Frontiers in veterinary science” This study found no significant difference in hair cortisol concentrations, a chronic stress indicator, between sows in farrowing crates and those in loose-housing systems.
16 citations
,
August 2017 in “Lupus” This case report and literature review highlights an unusual acne-like presentation of chronic cutaneous lupus erythematosus that doesn't improve with standard acne treatments, emphasizing the importance of considering CCLE in atypical acneiform eruptions.
16 citations
,
December 2012 in “The Clinical Journal of Pain” This study found that trichodynia is associated with both peripheral and central sensitization, potentially linked to hair cycle abnormalities and chronic pain through proinflammatory agents.
15 citations
,
January 2014 in “Hair therapy & transplantation” This study found that treatment with platelet-rich plasma showed some hair re-growth in patients with severe alopecia areata, but results were not sustained and treatment was associated with pain and discomfort.
14 citations
,
February 2020 in “Stem Cells International” This study reported that a single local subcutaneous infusion of mesenchymal stromal cells from the human umbilical cord promoted wound healing, improved blood circulation, and reduced wound size in patients with chronic wounds without significant adverse effects over one year.
13 citations
,
December 2021 in “Journal of Cellular and Molecular Medicine” This case report observed that treatment with human placental mesenchymal stromal cell-derived exosome-enriched extracellular vesicles may improve symptoms of chronic cutaneous graft-versus-host disease, including hyperpigmentation and skin ulcers, in a patient resistant to conventional therapies.
13 citations
,
January 2015 in “International Journal of Trichology” This study found that cadmium levels were significantly higher in women with chronic telogen effluvium compared to healthy controls, suggesting cadmium toxicity might contribute to this hair shedding condition.
12 citations
,
August 2021 in “International Journal of Biological Macromolecules” This study observed that Poria cocos polysaccharides and finasteride both reduced inflammation in chronic nonbacterial prostatitis in rats, but only Poria cocos polysaccharides reversed related changes in the gut microbiota.
12 citations
,
August 2020 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study found that most chronic alopecia areata patients treated with azathioprine, methotrexate, or cyclosporine continued treatment for at least 12 months, often requiring concurrent low-dose prednisolone.
12 citations
,
March 2018 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This article describes a case of frontal fibrosing alopecia in a patient with chronic lichenoid lupus erythematosus and notes the lack of similar documented cases in existing literature.
12 citations
,
November 2017 in “European Annals of Allergy and Clinical Immunology” This case report details a young female patient's experience of transient hair loss after starting omalizumab (anti-IgE) for chronic urticaria, noting that she continued the treatment for 10 months with positive outcomes despite this side effect.
12 citations
,
March 2004 in “International Journal of Dermatology” This case report describes a 16-year-old girl initially diagnosed with chronic telogen effluvium, later reassessed with Ludwig Stage 1 androgenetic alopecia, for which she began spironolactone treatment.
12 citations
,
March 2004 in “International Journal of Dermatology” A woman with X-linked chronic granulomatous disease developed lupus-like skin lesions, improved with treatment, suggesting a unique skin condition in carriers.