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The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.

A new gene mutation may allow some piebaldism patients to regain skin color in white patches.

Genetic data can predict male-pattern baldness with moderate accuracy, especially for early-onset cases in some European men.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Nonclassic congenital adrenal hyperplasia is a common genetic disorder that can cause a range of symptoms and requires personalized treatment.

The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Female cuckoo color differences are linked to their unique genes and help avoid male harassment.

The analysis of a large pilomatricoma revealed five distinct areas with different gene activity related to hair growth and tumor development.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Different hair protein amounts change the strength of keratin/chitosan gels, useful for making predictable tissue engineering materials.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Genetic factors affect hair loss, and molecular testing may help predict, diagnose, and treat it.

Dutasteride is more efficient than finasteride, but individual results vary.

Reversing female hair loss.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Certain genetic variations in the RAB5B gene are linked to a higher risk of polycystic ovary syndrome in Chinese Han women.

A new mutation in the CYP11B1 gene was found in a woman with mild hyperandrogenemia, a rare cause of non-classic congenital adrenal hyperplasia.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

The study found that giant pandas have more melanin in black hair follicles than white, with gene expression differences that could affect hair color and skin health.

The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.