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Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

Zebrafish need MYC and FGF to regenerate inner ear hair cells.

Different PCOS types respond uniquely to infertility treatments, with some having lower pregnancy rates and higher risks of complications.

Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

The Asiatic lion has very low genetic diversity and unique genetic traits, highlighting the need for its conservation.

Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

The review suggests new ways to classify ejaculation problems and recommends different treatments based on the type of issue.

The study found that mouse sweat glands develop before birth, mature after birth, and have specific keratin patterns.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

PCOS is common among Chinese women of reproductive age and linked to serious metabolic and reproductive issues, especially in obese women.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Lifestyle changes are the first step in treating infertility in PCOS, followed by medications like clomiphene and metformin, and then surgery if needed.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Two mouse mutations cause similar hair loss despite different skin changes.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.