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The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

New treatments targeting specific genes show promise for treating keratin disorders.

Minoxidil helps hair growth in 63.6% of alopecia patients, with 27.3% having excellent results.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Lower SHBG levels may increase the risk of PCOS.