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CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

The rhg mutation in mice affects the Oat gene, causing hair growth issues and other symptoms.

A genetic mutation in the EDA gene causes hypohidrotic ectodermal dysplasia in cats.

Genetic variants in PDE6H and LPAR6 cause vision impairment and hair loss in two Pakistani brothers.

Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Finasteride improves heart function and repairs damage after heart attack in mice.

TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.

PRP helps skin heal, possibly through special cells called telocytes.

FLRG and follistatin have different roles in wound healing.

Mitochondrial therapy and platelet-rich plasma therapy both stimulated hair regrowth in aging mice, with mitochondrial therapy showing similar effectiveness to plasma therapy.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Certain transporters are found in human hair follicles and may affect hair growth and loss.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.

EDA and EDAR are important for hair follicle development in cashmere goats and affect other related genes.

Kojyl cinnamate ester derivatives can promote hair growth by increasing adiponectin production in fat tissues.

Injecting CHIR-99021 into goose embryos improves feather growth by changing gene activity and energy processes.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.

lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.

The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.

Cantu syndrome, which causes excessive hair growth and skin issues, is due to a mutation in the ABCC9 gene, and understanding this could help develop new treatments for hair diseases.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.