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β-catenin in the dermal papilla is crucial for normal hair growth and repair.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Mutations in the DSG4 gene can cause a rare hair disorder similar to monilethrix.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Claudin-1 is important for the barrier function and growth of hair.

Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

COVID-19 can cause skin issues like chilblains and rashes, which may help in early detection, especially in patients without other symptoms.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.

Removing anthrax toxin receptor 1 in pigs prevents Senecavirus A infection and causes a rare disease similar to GAPO syndrome.

CD61 is important for mouse tooth cell growth and works through Lgr5.

Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.

Testosterone reduces key molecules needed for early pregnancy in rats.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.

Researchers found four genes that could help diagnose severe alopecia areata early.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

CD4+ skin cells may be precursors to basal cell carcinoma.

Recent selection on immune response genes was identified across seven ethnicities.

The research provides insights into hair follicle growth in forest musk deer by identifying key genes and pathways involved.

The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.

The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.

Ectodysplasin signaling is crucial for skin appendage development, requiring specific doses and durations.