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The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

Removing external lipids from hair reduces moisture and increases strength, while removing internal lipids decreases water permeability.

Human hair has more unsaturated fats inside than on the surface, and certain lipids may help bind the outer and inner layers together.

Surface and internal treatments can help prevent hair lipid loss during washing.

Hair texture changes with age due to varying levels of lipids.

All hair removal methods irritate underarm skin and cause dryness, with shaving being less irritating but more drying than plucking or waxing.

CCL5 is important for the hair growth potential of human dermal papilla cells.

Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.

Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.

Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.

Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.

Stem cells can create hair follicles, potentially treating permanent hair loss, and healthy skin and hair depend on mitochondrial function and special fats.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

PEVs improve minoxidil skin penetration, increasing hair growth.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Ozone reacts more with unwashed hair, producing compounds due to scalp oils, which could lower ozone exposure but increase exposure to reaction products.

The document concludes that dandruff and seborrheic dermatitis are linked to inflammation and skin changes, and treating them with specific shampoos can reduce these issues.

Minoxidil foam enters hair follicles and skin for hair growth.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.

Cationic polymers improved liposome stability and increased skin absorption of aciclovir and minoxidil.

Scalp skin barrier affects hair loss; personalized treatments needed.

Finasteride-loaded nanoparticles may help treat alopecia.

Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.

The article concludes that advancements in hair cosmetics require dermatologists to stay informed about products and their potential risks, including allergies and higher risks for hairdressers.