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CCCA is a scarring hair disorder mainly affecting people of African descent, needing better awareness and treatment.

Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.

The patient with both scarring and non-scarring hair loss showed complex immune reactions and improved with steroid treatment.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

Type 2 diabetes, bacterial scalp infections, and tight hairstyles like braids and weaves are linked to a higher risk of a scarring hair loss condition in African American women.

CCCA is a common scarring hair loss in African descent women, possibly linked to genetics, hair care practices, and health issues like diabetes.

COVID-19 may worsen hair loss in people with a certain type of scarring alopecia, but early treatment can help improve symptoms and hair regrowth.

Topical metformin helped regrow hair in two women with a hard-to-treat scarring hair loss condition.

Diagnose and manage CCCA with thorough history, exams, and labs; treat with anti-inflammatory agents, stress reduction, and stopping harmful hair practices.

Targeting cholesterol, fatty acids, fibrosis, and mast cells may help treat CCCA.

The document concludes that better treatments for CCCA are needed and more research is required to understand its causes related to hairstyling and genetics.

Hair loss in black women needs more research, early intervention, and community education.

CCCA is a common, progressive hair loss condition that may not always be linked to hair care practices and requires a biopsy for diagnosis.

The document concludes that central centrifugal cicatricial alopecia (CCCA) should be considered in African American men with vertex hair loss and scalp symptoms, and that prompt diagnosis and treatment can slow disease progression.

Black women with CCCA are more likely to have uterine fibroids.

Wearing a high-quality wig improved a woman's mood and life quality, and the authors suggest insurance should cover the cost of wigs.

More research is needed on CCCA in children, especially Black and Asian adolescents.

The authors maintain there is a significant link between vitamin D deficiency and central centrifugal cicatricial alopecia in Black patients, and call for more research on the topic.

Seborrheic dermatitis may contribute to the development of central centrifugal cicatricial alopecia.

CCCA can affect both genders and all ages, and it has a genetic component.

Low-dose metformin may help hair regrowth and reduce inflammation in CCCA.

Sebaceous glands are often preserved and PPARy expression is constant in some cases of Central Centrifugal Cicatricial Alopecia.

CCCA is a common hair loss condition in African American women, often inherited and influenced by hairstyling, with unique scalp features detectable by special tools.

New digital tools are improving the diagnosis and understanding of irreversible hair loss conditions.

Hair transplantation may work for some types of scarring alopecia, but results vary and more research is needed.

Chemical relaxers may cause scarring alopecia in black women.

Using CD123 to detect certain immune cells helps diagnose a type of hair loss condition.

Nonscarring alopecia has higher hair density than scarring alopecia, and hair density can help diagnose the type of alopecia.

Three characteristics of plasmacytoid dendritic cells help tell apart lupus-related hair loss from LPP.

Minoxidil may help with hair regrowth and disease stabilization in scarring alopecia, but side effects vary, needing more research for consistent safety and effectiveness.