Seborrheic Dermatitis as a Potential Trigger of Central Centrifugal Cicatricial Alopecia: A Review of Literature

September 2022 in “ Skin appendage disorders ”

Nwanneka Okwundu, Chiagoziem Ogbonna, Amy Mcmichael

seborrheic dermatitis central centrifugal cicatricial alopecia scarring alopecia chronic inflammation genetic factors autoimmune factors infectious factors idiopathic factors SD CCCA

TLDR Seborrheic dermatitis may contribute to the development of central centrifugal cicatricial alopecia.

This review explores the potential link between seborrheic dermatitis (SD) and central centrifugal cicatricial alopecia (CCCA), a common form of scarring alopecia. The etiology of CCCA remains uncertain, with genetic, autoimmune, infectious, and idiopathic factors considered as possible causes. SD is frequently observed in patients with CCCA, particularly among African American women, suggesting that the chronic inflammation associated with SD may contribute to the development of CCCA. The review hypothesizes that a history of SD could be a significant factor in the pathogenesis of CCCA.

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