Treatments for hair loss vary, but cell-based options may be the future.
375 citations,
June 2013 in “Biochimica et biophysica acta. Molecular cell research” Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
128 citations,
March 2006 in “American Journal of Pathology” Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
9 citations,
January 2017 in “International Journal of Trichology” The study suggests that mast cells might be involved in the hair loss condition telogen effluvium and could be a target for treatment.
8 citations,
January 2020 in “Skin Pharmacology and Physiology” Caffeine improves hair growth, thickness, and reduces shedding.
3 citations,
March 2022 in “Annals of Medicine” Hair shedding after COVID-19 is more linked to the disease's severity and inflammation rather than hormones, with women at higher risk.
2 citations,
February 1994 in “Archives of Dermatology” The debate focuses on the role of catagen and hair shedding mechanisms in telogen effluvium.
1 citations,
January 2016 in “Journal of stem cell research and medicine” Fat-derived stem cell therapies can potentially increase hair growth and thickness in people with hair loss.
1 citations,
January 2016 in “Journal of stem cell research and medicine” Fat-derived stem cell therapies can potentially increase hair growth and thickness in people with hair loss.
April 2021 in “Journal of Investigative Dermatology” Leontopodium alpinum extract may help reduce hair shedding by keeping hair in the growth phase longer.
759 citations,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
397 citations,
February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
221 citations,
July 2012 in “Proceedings of the National Academy of Sciences of the United States of America” BMAL1 controls skin cell growth and UV damage risk, peaking at night.
143 citations,
September 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
52 citations,
February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
45 citations,
April 2009 in “Journal of anatomy” Cat claws stay sharp by shedding their outer layer through microcracks formed during activities.
40 citations,
September 2017 in “F1000Research” Oral minoxidil effectively reduces hair shedding in women with CTE, with no major side effects.
40 citations,
May 2010 in “Australasian Journal of Dermatology” Chronic hair shedding may be caused by less variation in hair growth times and might stop on its own after several years.
12 citations,
August 2022 in “Biochemical Journal” Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
12 citations,
June 2006 in “Anais Brasileiros de Dermatologia” The study found average numbers for different types of hair follicles in the scalp and observed differences between men and women, suggesting reasons for more common hair shedding in women.
9 citations,
January 1978 in “Australian Journal of Biological Sciences” Flumethasone causes wool shedding in Merino wethers, with recovery in about 60 days.
7 citations,
November 2020 in “Experimental Dermatology” Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
6 citations,
May 2021 in “Aesthetic Surgery Journal” Higher cell number PRP improves hair density and diameter more than lower cell number PRP.
March 2024 in “GSC Advanced Research and Reviews” Different light affects cell functions and can help treat skin conditions.
March 2024 in “Stem cell research & therapy” Human dental pulp stem cell-conditioned medium, especially from hypoxic conditions, may help treat chemotherapy-induced hair loss and does not increase cancer risk.
January 2024 in “Indian Journal of Pharmaceutical Sciences” Peach kernel extract may promote hair growth by boosting cell growth in hair follicles.
December 2023 in “Journal of family medicine and primary care” Many people in Saudi Arabia experienced hair loss after COVID-19, especially women, those treated with antivirals, and those with a history of hair shedding.
October 1961 in “Archives of Dermatology” Reassurance is important for postpartum hair shedding as it likely won't cause complete baldness.
127 citations,
August 2016 in “The oncologist” Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.
59 citations,
February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.