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Early intervention is important for limited systemic sclerosis patients due to higher pain and ulceration risks.

Dermoscopy is useful for diagnosing and monitoring discoid lupus erythematosus by showing specific skin patterns.

This source reports that trastuzumab deruxtecan improves outcomes in HER2-positive and HER2-low metastatic breast cancer, emphasizing the need for careful adverse event monitoring, particularly for interstitial lung disease, and managing emetic risk to maximize benefits.

This study found that the oral contraceptive containing drospirenone (EE/DRSP) was as effective as EE/CPA in reducing acne lesions, sebum production, and hair growth in women with acne.

This study found that a mesenchymal stromal cell-derived regenerative extracellular matrix (rECM) significantly accelerated wound closure and improved healing in diabetic mice, also enhancing nerve and blood vessel formation compared to controls.

This study determined that the incidence of Discoid Lupus Erythematosus at the Government General Hospital, Chennai, from 2006 to 2008 was 1.7 per 1000, with localized and disseminated forms manifesting distinctive demographic and clinical patterns.

In a case report, this study identified a new genetic variant in a six-year-old girl from Saudi Arabia with hypotrichosis and juvenile macular dystrophy, expanding the understanding of the genetic spectrum of this rare condition in the region.

A 72-year-old man was diagnosed with a rare skin form of Rosai-Dorfman disease after years of misdiagnosis.

This study found that the vitamin D receptor in lampreys, which lack bones and hair, binds 1,25-dihydroxyvitamin D3 and may function to induce enzymes for detoxifying substances.

This study reports that Cur@CMCTS-Tk hydrogel effectively accelerated wound healing and tissue regeneration in rats by scavenging excess reactive oxygen species and protecting human fibroblasts from oxidative damage.

This review discusses the development and role of corneodesmosin in skin and hair follicle integrity, highlighting findings from mouse models and its connection to genetic diseases, with no new experimental results included.

This study suggests that RORα, RORβ, and RORγ mRNA expression in cashmere goat skin is related to different stages of hair follicle development, indicating a possible role in cycled cashmere growth.

This study found that both the natural ligand 1alpha,25(OH)(2)D(3) and the synthetic agonist LG190178 bind similarly to the vitamin D receptor's coregulator motifs, suggesting similar biological functions.

The researchers investigated a Maine Coon cat with suspected classical Ehlers-Danlos Syndrome and discovered a heterozygous deletion in the COL5A1 gene, underscoring the value of whole-genome sequencing for precise veterinary diagnostics.

This study found that the vitamin D-VDR system is crucial for mineral and bone metabolism post-weaning and identified missense mutations in 1alpha-hydroxylase causing type I rickets.

This study reported that a newly developed hydrogel patch, designed to recruit regulatory T cells through ROS-triggered release of CCL22, improved wound healing and hair follicle regeneration in a diabetic mouse model by scavenging ROS, thereby protecting Tregs and suppressing Th17 cells.

This study found that the solid self-nanoemulsifying drug delivery system improved the oral bioavailability of carvedilol significantly compared to the drug alone, enhancing its solubility, dissolution, AUC, and Cmax.

This study found that Fraser's Dolphin, a tight-skinned mammal, can regenerate complex skin architecture with minimal scarring after large full-thickness wounds, even in high-tension environments, offering insights into regenerative healing mechanisms typically obscured by fibrotic responses.

This study found that carbon dots derived from fucoidan effectively inhibit Enterococcus faecalis and its biofilm, offering a promising approach for managing biofilm-associated persistent endodontic infections.

This case report highlights a family member with a confirmed diagnosis of hypotrichosis with juvenile macular dystrophy due to a CDH3 gene mutation, emphasizing the importance of genetic testing for accurate counseling.

This study suggests that for dermatomyositis patients with minimal skin disease activity, further improvement in cutaneous symptoms may not translate into better quality of life, highlighting a need to revise trial endpoints.

This article discusses the evaluation of minimal residual disease in childhood acute lymphoblastic leukemia using molecular methods and reports no new findings.

This study reports that in mice, CaR plays a critical role in sensing the epidermal Ca2+ gradient, influencing keratinocyte differentiation, and affecting epidermal development.

This study found that using electronic healthcare record data can provide valuable early insights into the clinical context of about half of the new safety signals evaluated within a regulatory environment.

This review discusses the confusion and misuse of Polygoni Multiflori Radix, Cynanchi Wilfordii Radix, and Cynanchi Auriculati Radix in Korea, highlighting their plant origins, uses, and toxicities, without providing new clinical results.

This study demonstrated that a metric based on rotational echo intensity in 2H magic-angle spinning NMR can derive kinetic information for conformational exchange without complex modelling, achieving activation barriers consistent with prior findings.

This issue of the Journal of Cosmetic Dermatology reviews several topics, including the use of radiofrequency in aesthetics and cannabinoids for skin diseases, but presents no new research findings.

This case report detailed a 71-year-old male with Cronkhite-Canada syndrome and associated membranous nephropathy, who showed a significant improvement in skin and gastrointestinal symptoms, and remission of nephropathy, after treatment with rituximab, cyclosporine, and azathioprine.