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420-450 / 1000+ resultsresearch Distinct transcriptomic landscapes of cutaneous basal cell carcinomas and squamous cell carcinomas
This study identified significant gene expression differences in human basal cell carcinoma, including up-regulation of zinc finger encoding genes, which are not entirely reflected in current mouse models.
research Hair Growth Promotion Activity of Bacillus Cereus Strain, An Endophytic Bacterium, Isolated from Eclipta Prostrata (L.) L
research 84: Cannabinoid use for symptom management in epidermolysis bullosa
In this survey study, 44% of epidermolysis bullosa patients who tried cannabinoids reported effective symptom management, particularly pain relief, but concerns about cost, stigma, and accessibility remain significant. Further research is necessary to confirm these findings and optimize cannabinoid therapies for EB.
research Clobetasol/minoxidil
research Cyproteronacetat zur topischen Therapie androgenabhängiger Erkrankungen
This study found that CPA-loaded nanoparticles, particularly SLN formulations, increased CPA epidermal penetration compared to a conventional cream and may reduce side effects in treating androgen-dependent conditions.
research Neuroimaging Findings in Congenital Biotinidase Deficiency: A Case Report
This case report describes a six-year-old child with congenital biotinidase deficiency whose symptoms, including breathlessness, alopecia, and hearing loss, were reversed with biotin supplementation.
research A Case of Cronkhite-Canada Syndrome Presenting with Hematochezia
This article reports on a patient case of Cronkhite-Canada syndrome, detailing symptoms and diagnostic findings, and reviews the syndrome's characteristics without presenting new clinical data.
research Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.
This study found that AtT-20 pituitary cells with higher cAMP-dependent kinase activity had larger calcium currents and significantly increased beta-endorphin release compared to cells with lower kinase activity.
research Cronkhite-Canada syndrome associated withmyelodysplastic syndrome
This study reports the first documented case of Cronkhite-Canada syndrome in a patient with myelodysplastic syndrome, where corticosteroids dramatically improved the patient's condition.
research CPK1 activates CNGCs through phosphorylation for Ca2+ signaling to promote root hair growth in Arabidopsis
This study discovered that calcium dependent protein kinase 1 (CPK1) directly activates cyclic nucleotide-gated channels 5, 6, and 9, promoting root hair growth in Arabidopsis by regulating Ca²⁺ signaling.
research Calcipotriol/dithranol
research Efficacy and Safety of Cinobufacin Combined with Chemotherapy for Advanced Breast Cancer: A Systematic Review and Meta‐Analysis
This study found that Cinobufacin combined with chemotherapy improved clinical outcomes in breast cancer patients and reduced certain side effects compared to chemotherapy alone.
research Hair Cortisol and Cushing's Disease
research 272 Structural changes in human skin after topical application of glucocorticoids assessed by in vivo imaging technologies
This study evaluated the effects of topical glucocorticoids on human skin using non-invasive imaging methods and observed changes such as alterations in skin layer thickness, keratinocyte size, and collagen and elastin signal intensity.
research Inhibition of CCAAT/Enhancer Binding Protein Family DNA Binding in Mouse Epidermis Prevents and Regresses Papillomas
This study found that inhibiting C/EBP transcription factors in mouse skin reduced papilloma formation and caused systemic hair loss, suggesting C/EBP may be a potential therapeutic target.
research Cover Feature: Electronic Circular Dichroism Imaging (ECD i ) Casts a New Light on the Origin of Solid‐State Chiroptical Properties (Chem. Eur. J. 4/2022)
This study found that synchrotron radiation ECD imaging provides new insights into solid-state Finasteride by highlighting the significant role of anisotropy in local domains for chiroptical measurements.
research The necessity of investigations to clarify sex and racial disparities in pathophysiology of Long COVID
More research is needed to understand sex and racial differences in long COVID.
research CuCS/Cur composite wound dressings promote neuralized skin regeneration by rebuilding the nerve cell "factory" in deep skin burns
In this study, the researchers developed a novel wound dressing incorporating copper-doped calcium silicate and curcumin, which significantly promoted nerve and blood vessel regeneration in deep burn wounds, emphasizing the crucial role of bioactive chelation in neuralized skin repair.
research A highly resistant structure between the cuticle and the cortex of human hair. II. CARB, a penetration barrier
This study found that a highly resistant structure, located at the interface between the cuticle and cortex of human hair, acts as a penetration barrier, which the authors propose to name the "cuticle anchored resistant base" or CARB.
research Ca 2+ -mediated protein citrullination regulates proliferation in the regenerating and malignant CNS
This study found that Ca²⁺ signaling and peptidylarginine deiminase enzymes play a crucial role in activating neural stem cells in response to injury in zebrafish, suggesting potential therapeutic targets for CNS injuries and cancer.
research Calcium, Cobalt, Strontium, and Cerium-Based Binary Silicate Bioactive Nanoglasses: Rational Comparison in Bioactive Properties for Optimizing Tissue Repair Applications
This study synthesized and compared single-ion doped silicate bioactive glass nanoparticles for tissue repair, finding that BSr and BCe were most effective in accelerating wound healing and restoring vasculature, with BSr particularly reducing inflammation and BCo enhancing hair follicle regeneration but with limited biosafety window.
research Role of -catenin in Epidermal Stem Cell Expansion, Lineage Selection, and Cancer
This review examines beta-catenin's role in stem cell renewal, lineage selection, and tumor formation in the epidermis and reports no new experimental findings.
research Synthetically programmed antioxidant delivery by a domesticated skin commensal
This study developed a genetic toolbox to engineer Cutibacterium acnes for dermal applications, successfully creating a strain that secretes antioxidants to reduce oxidative stress in a UV stress model.
research Effects of Teaching Thinking Skills on SAT Scores.
This study found that NFIB and STAT5 work together to regulate mammary-specific genetic programs in mice, with their combined absence hindering functional alveoli formation.
research Dermatoscopic features of central centrifugal cicatricial alopecia
This study found that a peripilar white gray halo around hair emergence is a highly specific and sensitive dermatoscopic feature for diagnosing central centrifugal cicatricial alopecia in African American patients with mild central thinning.
research Discrepancies in safety reporting for chronic back pain clinical trials: an observational study from ClinicalTrials.gov and publications
This study reports that discrepancies in adverse event reporting for clinical blood pressure trials undermine the reliability of safety data, suggesting a need for standardized reporting guidelines to improve trustworthiness.
research Distinct transcriptomic landscapes of cutaneous basal cell carcinomas and squamous cell carcinomas
This study found that human basal cell and squamous cell carcinomas have distinct gene expression patterns, with specific up-regulation of zinc finger encoding genes in basal cell carcinoma.
research SnapshotDx Quiz: May 2020
This study reported that specific inhibition of the classical complement pathway with BIVV009 prevented C3 deposition along the dermal-epidermal junction in bullous pemphigoid, reflecting its potential efficacy.
research Cronkhite-Canada syndrome: A case report and literature review
In this case report, a 72-year-old female with Cronkhite-Canada syndrome showed significant improvement in symptoms and gastrointestinal polyps after hormone therapy and additional treatment.