Efficacy and Safety of Cinobufacin Combined with Chemotherapy for Advanced Breast Cancer: A Systematic Review and Meta-Analysis
January 2020
in “
Evidence-based Complementary and Alternative Medicine
”
Studysummary This study found that Cinobufacin combined with chemotherapy improved clinical outcomes in breast cancer patients and reduced certain side effects compared to chemotherapy alone. Our plain-language summary of this paper — not a Tressless recommendation.
This systematic review and meta-analysis assessed the efficacy and safety of combining Cinobufacin with chemotherapy for advanced breast cancer, involving 1,331 patients across 16 randomized controlled trials. The combination treatment improved clinical efficacy, quality of life, and reduced tumor markers (CA125, CA153, and CEA) compared to chemotherapy alone, while also decreasing adverse reactions like gastrointestinal issues, liver and kidney damage, and hair loss. Despite these positive findings, the study acknowledged variability due to differences in chemotherapy methods and the quality of the studies, suggesting the need for further research on different dosage forms of Cinobufacin.
