26 citations
,
February 1998 in “Chemico-Biological Interactions” This review discusses recent molecular biology advances in the human phenol sulfotransferase gene family and reports no new results; the authors highlight its relevance for studies of endogenous and xenobiotic metabolism.
11 citations
,
November 1991 in “Journal of Neuropathology & Experimental Neurology” This study found that brindled mottled mice, a model of Kinky hair syndrome, exhibited abnormal development of catecholamine neurons, with increased TH-immunoreactive neurons and altered neurochemical profiles compared to controls.
2 citations
,
May 2021 in “Molecules” This study reports that the metanephrine content was significantly higher in patients with alopecia areata compared to those without the condition.
May 2026 in “Nature Communications” In this study, researchers identified that keloid fibroblasts respond to neurotransmitters from catecholaminergic nerves by producing bone matrix proteins, mediated by β1-adrenergic receptor activation, leading to fibro-osseous reprogramming; blocking this signaling in a rodent model prevented the development of keloid-like pathology.
375 citations
,
July 2006 in “Journal of Investigative Dermatology” This review discusses the brain-skin connection, the skin's role in stress response, and highlights unmet challenges in understanding stress-induced skin inflammation but reports no new experimental findings.
146 citations
,
January 2004 in “Hormones” This review explores the complex endocrine functions of human skin and its role as a peripheral endocrine organ, but reports no new clinical results.
109 citations
,
October 2007 in “Journal of pineal research” This study suggests that melatonin plays a role in hair follicle function by modulating growth and pigmentation, and it may act as a protective agent in active hair growth phases.
43 citations
,
March 2011 in “Journal of psychosomatic research” This study found that children with alopecia areata experienced more stressful life events and excreted higher levels of catecholamines compared to healthy siblings.
38 citations
,
January 2014 in “International Journal of Endocrinology” This review highlights that children with adrenal disorders may experience neurological and psychiatric symptoms, with potential long-term cognitive and behavioral effects from excess glucocorticoids.
11 citations
,
April 2013 in “SpringerPlus” This study reports that melanocytes form a defined photoresponsive network in the skin that reads environmental light cycles and may influence the sleep-waking cycle similar to the pineal gland.
5 citations
,
August 2005 in “Anatomy and Embryology” This study found that concentrated clusters of noradrenergic nerve fibers form a longitudinal linear system in rat skin, particularly innervating arrector pili muscles.
3 citations
,
September 1980 in “Experientia” In this study, the pharmacological action of dobutamine on rabbit retinae was found to be distinct from that of other dopamine analogs like apomorphine and N-methyl-dopamine.
1 citations
,
November 2021 in “American Journal of Clinical Pathology” In this study, autopsies of children who suffered fatal abuse revealed stress-associated markers like telogen effluvium and thymus involution, which may help pathologists identify chronic abuse cases.
March 2026 in “Wiadomości Lekarskie” This narrative review explores how psychological stress may contribute to premature skin aging by affecting dermal collagen and elastin remodeling through neuroendocrine, molecular, and cellular pathways, highlighting potential therapeutic targets to preserve skin structure and function.
December 2025 in “Frontiers in Immunology” This review highlights that disturbances in neuroimmune communication, particularly between sympathetic nerves and macrophages, may contribute to autoimmune diseases like rheumatoid arthritis and type 1 diabetes, and suggests potential therapeutic avenues by restoring this communication in preclinical and early clinical studies.
May 2026 in “JID Innovations” This study found a significant overlap between gene expression signatures of alopecia areata and certain chronic inflammatory skin disorders, suggesting shared biological processes may drive their co-occurrence and providing a foundation for future research into distinct comorbid subtypes.
October 2023 in “Journal of the Endocrine Society” This study reported a rare case where a pheochromocytoma produced ACTH, leading to cyclic Cushing syndrome, and underscores the importance of considering this possibility in cases of ACTH-dependent hypercortisolism with an adrenal mass.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This case report reveals a diagnosis of scurvy in a 19-year-old woman, emphasizing the importance of considering vitamin C deficiency in patients with dietary restrictions presenting with specific skin and gum symptoms.
11 citations
,
January 1980 in “Southern Medical Journal” This study found that minoxidil effectively manages various types of severe hypertension but can cause side effects such as sodium retention and tachycardia.
5 citations
,
January 1984 in “Journal of psychosomatic obstetrics and gynecology/Journal of psychosomatic obstetrics and gynaecology” This study found that treatment with cyproterone acetate and ethinylestradiol in hirsute women reduced testosterone and androstenedione levels, decreased hair growth, and increased cortisol levels without changing catecholamine excretion.
May 2025 in “Journal of the ASEAN Federation of Endocrine Societies” This case report discusses a patient with VHL-associated paraganglioma, highlighting the importance of genetic testing and monitoring in those with VHL disease, due to high mutation penetrance and associated risks.
November 2025 in “Molecules” This review examines recent advancements in green and emerging microextraction techniques, such as SPME and DLLME, for more sustainable hormone detection in biological samples, emphasizing environmentally friendly solvents and bioanalytical applications.
105 citations
,
February 2011 in “The Journal of Clinical Endocrinology & Metabolism” Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.
82 citations
,
August 2006 in “Pharmacology, Biochemistry and Behavior” This review proposes focusing on relationships between neuroactive steroids and psychiatric disorder symptoms, rather than relying on traditional disorder classifications, and reports no new clinical findings.
16 citations
,
May 1998 in “International Journal of Dermatology” This study found that elevated serum cortisol levels and other immunological changes are significantly involved in the active phases of psoriasis eruptions.
This chapter reviews various types of aromatic compounds and provides references, but reports no new experimental results.
252 citations
,
January 2008 in “Trends in Endocrinology and Metabolism” This review discusses the protective and stress-buffering roles of melatonin in skin functions and structures but does not present new clinical findings.
197 citations
,
January 2019 in “Neuropsychopharmacology” This review discusses sex differences in the neuroendocrine response to stress, focusing primarily on rodent studies, and highlights open questions about the roles of gonadal hormones and sex chromosomes.
125 citations
,
September 2001 in “The FASEB Journal” This study demonstrated that stress inhibited hair growth in mice, likely through substance P-dependent activation of immune cells, highlighting a brain-hair follicle connection.
108 citations
,
October 2004 in “Anesthesiology” This review discusses surgical factors that may increase the risk of developing complex regional pain syndrome and describes potential preventive techniques but presents no new clinical results.