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GlossaryCatecholamines

hormones from adrenal glands involved in stress response

Catecholamines are a group of hormones produced by the adrenal glands, which sit on top of the kidneys. These hormones, including adrenaline (epinephrine), noradrenaline (norepinephrine), and dopamine, play a crucial role in the body's stress response by increasing heart rate, blood pressure, and blood glucose levels. They are also involved in the regulation of mood, attention, and the fight-or-flight response.

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Cloning of the Human Phenol Sulfotransferase Gene Family: Three Genes Implicated in the Metabolism of Catecholamines, Thyroid Hormones, and Drugs

research Cloning of the Human Phenol Sulfotransferase Gene Family: Three Genes Implicated in the Metabolism of Catecholamines, Thyroid Hormones, and Drugs

26 citations, February 1998 in “Chemico-Biological Interactions”

Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.

research Serial Hydrolysis for the Simultaneous Analysis of Catecholamines and Steroids in the Urine of Patients with Alopecia Areata

2 citations, May 2021 in “Molecules”

A new method was created to analyze certain chemicals in the urine of alopecia areata patients, revealing they have higher metanephrine content. This method can also be used for other related diseases.

research Neuroimmunology of Stress: Skin Takes Center Stage

375 citations, July 2006 in “Journal of Investigative Dermatology”

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

research The Human Skin as a Hormone Target and an Endocrine Gland

146 citations, January 2004 in “Hormones”

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

research Melatonin and the Hair Follicle

109 citations, October 2007 in “Journal of pineal research”

Melatonin helps regulate hair growth and protects the hair follicle from stress.

research Environmental Stress But Not Subjective Distress in Children or Adolescents With Alopecia Areata

43 citations, March 2011 in “Journal of psychosomatic research”

Kids with alopecia areata may experience more stress but not necessarily feel more anxious or depressed than others.

research Adrenal Disorders and the Pediatric Brain: Pathophysiological Considerations and Clinical Implications

38 citations, January 2014 in “International Journal of Endocrinology”

Adrenal disorders can cause lasting brain and behavior issues in children.

research The Melanocyte Photosensory System in Human Skin

11 citations, April 2013 in “SpringerPlus”

Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.

research Effects of Dobutamine on Cyclic AMP Accumulation Induced by the Stimulation of Dopamine Receptors in Rabbit Retina In Vitro

3 citations, September 1980 in “Experientia”

Dobutamine does not mimic dopamine at therapeutic doses but may at very high concentrations; microfilaments, not microtubules, are important for wound healing in Xenopus embryos.

research Morphologic Markers of Acute and Chronic Stress in Child Abuse

1 citations, November 2021 in “American Journal of Clinical Pathology”

The conclusion is that certain physical signs in the body can indicate past acute and chronic stress, which may help in child abuse investigations.

research Cyclic Cushing Syndrome Caused By An ACTH-Producing Pheochromocytoma

October 2023 in “Journal of the Endocrine Society”

A woman's cyclic Cushing syndrome was caused by a tumor in her adrenal gland that produced ACTH.

research Scurvy: A Forgotten Illness?

July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Scurvy still occurs today and can be diagnosed by symptoms like gum bleeding and a specific rash, confirmed by low vitamin C levels.

research Minoxidil

11 citations, January 1980 in “Southern Medical Journal”

Minoxidil effectively treats severe hypertension but has notable side effects.

research Anti-Androgen Treatment of Hirsute Women: A Study on Stress Responses

5 citations, January 1984 in “Journal of psychosomatic obstetrics and gynecology/Journal of psychosomatic obstetrics and gynaecology”

The treatment reduced hair growth and testosterone in women with excess hair and had some effects on stress responses.

research Telogen Effluvium as a Clinical Presentation of Human Immunodeficiency Virus Infection

5 citations, April 2002 in “The American Journal of Medicine”

Hair loss can be an early sign of HIV infection.

research Treatment of Obstructive Sleep Apnea Improves Cardiometabolic Function in Young Obese Women with Polycystic Ovary Syndrome

105 citations, February 2011 in “The Journal of Clinical Endocrinology & Metabolism”

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

research Neurosteroids, Neuroactive Steroids, and Symptoms of Affective Disorders

82 citations, August 2006 in “Pharmacology, Biochemistry and Behavior”

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

research Immunoregulatory Mechanisms and Stress Hormones in Psoriasis (Part 1)

16 citations, May 1998 in “International Journal of Dermatology”

Stress hormones like cortisol may trigger psoriasis flare-ups.

research Melatonin in the Skin: Synthesis, Metabolism, and Functions

252 citations, January 2008 in “Trends in Endocrinology and Metabolism”

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

research Sex Differences in the Hypothalamic–Pituitary–Adrenal Axis’ Response to Stress: An Important Role for Gonadal Hormones

197 citations, January 2019 in “Neuropsychopharmacology”

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Indications for a Brain-Hair Follicle Axis: Inhibition of Keratinocyte Proliferation and Up-Regulation of Keratinocyte Apoptosis in Telogen Hair Follicles by Stress and Substance P

research Indications for a Brain-Hair Follicle Axis: Inhibition of Keratinocyte Proliferation and Up-Regulation of Keratinocyte Apoptosis in Telogen Hair Follicles by Stress and Substance P

125 citations, September 2001 in “The FASEB Journal”

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

research Preventing the Development of Complex Regional Pain Syndrome After Surgery

108 citations, October 2004 in “Anesthesiology”

Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.

research Minoxidil in Severe Hypertension: Value When Conventional Drugs Have Failed

50 citations, September 1975 in “American Heart Journal”

Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.

research Localization of Minoxidil Sulfotransferase in Rat Liver and the Outer Root Sheath of Anagen Pelage and Vibrissa Follicles

46 citations, January 1991 in “Journal of Investigative Dermatology”

Minoxidil works in liver and outer hair root sheath for hair growth.

$Long-Term Treatment of Refractory Hypertensive Patients With Minoxidil$

research Long-Term Treatment of Refractory Hypertensive Patients With Minoxidil

43 citations, May 1978 in “JAMA”

Minoxidil controls blood pressure but may cause kidney damage and needs diuretics to prevent swelling.

research Effect of Minoxidil on Blood Pressure and Hemodynamics in Severe Hypertension

34 citations, January 1977 in “American Journal of Cardiology”

research Psychotropic Medication and Drug-Related Alopecia

30 citations, May 1991 in “Psychosomatics”

Some psychiatric medications can cause reversible hair loss.