research Evidence-Based Medicine in Obstetrics and Gynecology
Accurate diagnosis and timely, tailored treatments improve outcomes in obstetrics and gynecology.
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research Sodium Valproate: Doctor Jekyll and Mister Hyde
Sodium valproate is effective in treating epilepsy, especially in patients who don't respond to other medications.
research Development of a Non-Parametric Population Pharmacokinetics Model and Bayesian Estimator for Tacrolimus in Tunisian Renal Transplant Patients
The model and estimator can predict drug exposure in kidney transplant patients well.
research Polycystic Ovary Syndrome and Cardiovascular Disease
PCOS increases the risk of heart disease and type 2 diabetes in women.
research Psoriasis
Psoriasis treatments range from topical creams to systemic medications with serious side effects, and while treatments can manage symptoms, there is no cure.
research Non-Binary or Genderqueer Genders
The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.
research Surface Modification and Endothelialization of Biomaterials as Potential Scaffolds for Vascular Tissue Engineering Applications
Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.
research Polycystic Ovary Syndrome and Cardiovascular Disease: A Premature Association?
While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.
research COVID-19 and Endocrine and Metabolic Diseases: An Updated Statement from the European Society of Endocrinology
People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.
research Cutaneous Effects of the Most Commonly Used Antidepressant Medication, the Selective Serotonin Reuptake Inhibitors
Antidepressants called SSRIs can cause skin problems, bleeding risk, and other side effects.
research Minoxidil Therapy in Children with Severe Hypertension
Minoxidil helps lower high blood pressure in kids, but can cause fluid retention and hair growth.
research Treatment of Refractory Hypertension
Most patients with hard-to-treat high blood pressure can be managed effectively with various treatments, but no single treatment is perfect.
research Metabolomic Biomarkers in Women with Polycystic Ovary Syndrome: A Pilot Study
Certain metabolites are lower in women with PCOS and could be potential markers for the condition.
research Hypertensive Crisis Associated with St. John’s Wort
St. John's Wort can cause dangerous high blood pressure if taken with certain foods.
research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Straight Hair Associated with Interferon-Alpha Plus Ribavirin in Hepatitis C Infection
ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.
research The Frequency of Metabolic Syndrome Is Higher Among Brazilian Women With PCOS, Menstrual Irregularity, and Hyperandrogenism
Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research Possible Contribution of Chronobiology to Cardiovascular Health
Understanding and tracking our body's natural daily rhythms could help improve heart health.
research Comparative Evaluation of Biomarkers of Inflammation Among Indian Women With Polycystic Ovary Syndrome Consuming Vegetarian vs. Non-Vegetarian Diet
Vegetarian Indian women with PCOS have higher inflammation levels than non-vegetarians.
research High-Sensitivity C-Reactive Protein Levels and Their Relationship with Components of Polycystic Ovary Syndrome in Indian Adolescent Women with PCOS
Higher hs-CRP levels in Indian adolescent women with PCOS are more related to BMI than PCOS itself.
research Apocrine Sweat Gland Obstruction by Antiperspirants Allowing Transdermal Absorption of Cutaneous Generated Hormones and Pheromones as a Link to the Observed Incidence Rates of Breast and Prostate Cancer in the 20th Century
The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
research Aggressive Squamous Carcinomas of the Scalp
Aggressive scalp squamous cell carcinomas have a high death rate and need early, strong treatment.
research Enhanced Viability and Neural Differentiation Potential in Poor Post-Thaw Human Adipose-Derived Stem Cells by Agarose Multi-Well Dishes and Spheroid Culture
Spheroid culture in agarose dishes improves survival and nerve cell growth in thawed human fat-derived stem cells.
research Oral Administration of Low-Dose Bisphenol A Promotes Proliferation of Ventral Prostate and Upregulates Prostaglandin D2 Synthase Expression in Adult Rats
Low doses of BPA can increase prostate growth and change hormone levels in adult rats.
research A Connection Between the Mitochondrial Permeability Transition Pore, Autophagy, and Cerebral Amyloidogenesis
Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.
research Cardiovascular Effects of Ingesting Topical Minoxidil in Pediatric Patients
Ingesting minoxidil can cause serious heart issues; keep away from children and improve packaging.
research Psychosomatic Factors in Dermatology: Special Perspectives for Application in Clinical Practice
Doctors should consider psychological factors when treating skin conditions and work with mental health experts.
research Alterations in Transcriptome and Antioxidant Activity of Naturally Aged Mice Exposed to Selenium-Rich Rice
Eating selenium-rich rice improved antioxidant activity and signs of aging in mice.
research Recommendations for Endocrine Treatment of Patients with Gender Dysphoria
The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.