May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study identified 4,942 differentially expressed genes and key candidate genes involved in the hair follicle development and cashmere quality differences between Jiangnan and Changthangi goats, highlighting potential molecular targets for genetic improvement of cashmere goats.
April 2024 in “Human genomics” This study identified MPB susceptibility genes and potential drug candidates that may help uncover molecular mechanisms and address male-pattern baldness.
April 2012 in “Encyclopedia of Life Sciences” This review discusses recent genome-wide association studies identifying novel candidate genes for various forms of alopecia, providing insights into their pathogenesis and molecular mechanisms, but reports no new clinical results.
September 2003 in “Journal of the Royal Society of Medicine” The book is a comprehensive guide for forensic practitioners and exam candidates.
September 2002 in “Dermatologic Surgery” The author reports that an evaluation system for assessing candidacy in alopecia-reducing procedures significantly decreased unsuitable surgeries while maintaining consistently good outcomes.
February 2023 in “European Journal of Medical Research” This study identified several drugs that may be potential candidates for repurposing as anti-hyperhidrosis treatments, based on their association with hypohidrosis or anhidrosis in the FDA Adverse Event Reporting System.
13 citations
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August 2002 in “Dermatologic Surgery” This paper introduces Follicular Unit Extraction and reports the FOX Test can identify suitable candidates, with about 25% of patients being ideal and 35% being good candidates for the procedure.
3 citations
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July 2011 in “Hair transplant forum international” This abstract discusses the exclusion of cardiovascular and cerebrovascular disease patients from hair transplantation candidates and highlights the potential challenge of obtaining detailed medical histories in busy clinical settings, without reporting new results.
3 citations
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September 2002 in “Dermatologic Surgery” This study presents an evaluation system that helps hair restoration surgeons better identify candidates for alopecia-reducing procedures, resulting in more consistently good outcomes by excluding poor and borderline candidates.
2 citations
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January 2022 in “Stem cell biology and regenerative medicine” This review discusses the potential of extracellular vesicles from various sources as promising candidates for hair growth stimulation but notes that clinical trials are needed to confirm their effectiveness and safety.
2 citations
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October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” This study reports promising preliminary trends in the safety and efficacy of a botanical drug candidate for pediatric alopecia areata, but conclusive results are not yet available.
September 2022 in “Medical Mycology” This study found that three protocols for generating Titan cells in vitro from Candida neoformans vary in their kinetics and transcriptomic profiles, pointing to differences which could impact further research.
May 2021 in “Letters in Applied NanoBioScience” This study used computational methods to identify pranlukast and mirabegron as promising candidates for repurposing against diabetes due to their good binding interactions with the DPP-IV target.
June 2003 in “Clinical orthopaedics and related research” This case study reports a rare instance of Majocchi's granuloma caused by Candida, highlighting the patient's diabetes mellitus and kidney transplant as predisposing factors for the infection.
December 2010 in “Cancer Prevention Research” This study provides evidence supporting the feasibility of presurgical, window-of-opportunity models to evaluate the preventive potential of candidate agents in cancer, using cases from breast, prostate, and colorectal settings.
January 2001 in “Current problems in dermatology” This review discusses the evolution of hair transplantation techniques and provides guidelines for determining suitable candidates for surgery, but reports no new clinical results.
17 citations
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October 2020 in “South African Medical Journal” This review highlights that fungal co-infections, notably with Aspergillus and Candida, are common in hospitalized COVID-19 patients, but their impact on disease outcomes remains unclear, indicating a need for further research.
14 citations
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May 1987 in “Archives of Dermatology” This article discusses tissue-expansion augmented scalp reduction as a surgical option for cicatricial alopecia patients who are otherwise not candidates for traditional hair replacement techniques, but it reports no new clinical results.
12 citations
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December 2016 in “Medical Hypotheses” This research suggests that the enzyme Phospholipase D from E. coli is a strong candidate as the underlying cause of benign prostatic hyperplasia, potentially mediated by its conversion to lysophosphatidic acid in the prostate.
2 citations
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December 2020 in “Frontiers in genetics” In this study, the researchers identified the SPEF2 and PRLR genes as potential candidates associated with feather rate phenotypes in Shouguang chickens through combined genome-wide association and differential expression analyses.
1 citations
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October 2023 in “Animals” This study explored the genetic basis of fiber diameter in alpacas, identifying candidate genomic regions including four significant areas on VPA6, VPA9, VPA29, and an unassigned scaffold, using whole genome association analysis and a custom SNP microarray.
1 citations
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December 2022 in “Biomolecules & therapeutics” This study found that a long-term astrocyte culture model can effectively study astrocyte senescence and suggests minoxidil as a potential candidate to regulate brain aging by normalizing dysregulated gene expression in aged astrocytes.
September 2026 in “British Journal of Dermatology” This study identified 11 genes associated with non-syndromic hereditary hypotrichosis in a Chinese cohort and proposed a preliminary framework for phenotype-driven candidate-gene prioritization to aid clinical evaluation.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, in silico analysis identified Saponin Re and Emodin as promising candidates for topical treatment of androgenetic alopecia, with Biochanin A having the most favorable safety profile among the tested compounds.
In this study, researchers optimized the soft drug AR antagonist 14-P1 to create candidate 39, which demonstrated effective AR antagonism and safety in a hair-growth mouse model, showing similar efficacy to pyrilutamide but with quicker onset and a lower risk of systemic toxicity.
In a hair-growth mouse model, this study reported that the novel AR antagonist candidate 39, derived from structural optimization of 14-P1, achieved similar efficacy to pyrilutamide with faster response and maintained safety, demonstrating potent AR antagonism and favorable pharmacokinetics with lower systemic toxicity risk.
In this study, a dual soft drug design strategy improved the AR antagonist candidate 39, showing potent AR antagonism and good safety in a mouse hair-growth model, with similar efficacy to pyrilutamide but faster response.
March 2026 in “Preprints.org” This review suggests that the compound DRDE-07, originally a sulphur-mustard countermeasure candidate, could potentially be repurposed for skin protection due to its compatibility with pathways involved in oxidative stress and inflammation, though further experimental study is needed to confirm its therapeutic applicability in dermatology.
February 2026 in “International Journal of Molecular Sciences” In this study, researchers identified 47 proteins associated with male pattern baldness severity and prioritized five candidate genes, including druggable CD38, suggesting new non-hormonal targets for therapeutic development.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports the discovery of LX-38, a novel non-steroidal drug candidate that may offer safer treatment for conditions like Benign Prostatic Hyperplasia by avoiding hormonal side effects associated with current therapies.