research Clinical Application of 5α-Reductase Inhibitors
5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.
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research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research Anti-Cancer Properties of Olive Oil Secoiridoid Phenols: A Systematic Review of In Vivo Studies
Olive oil compounds may help prevent cancer in animals, but human results are mixed.
research Finasteride for Prostatic Disease: An Updated and Comprehensive Review
Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.
research A Cornerstone of Hematological Science
The document concludes that accurately identifying leukemia types is crucial, and the risks of cancer from finasteride need careful evaluation against its benefits.
research Trailing the Path to Preventive Oncology
Preventing cancer involves lifestyle changes, vaccinations, early screening, and understanding cancer's molecular basis.
research The Vitamin D Receptor as Tumor Suppressor in Skin
Vitamin D and its receptor may help prevent skin cancer.
research Selenium or No Selenium: That Is the Question in Tumor Patients - A New Controversy
There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.
research 5-Alpha-Reductase Inhibitors and Combination Therapy
Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.
research Finasteride
Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.
research Clinical Pearls in Men's Health
The conclusion is that individualized treatment and proper medication use are crucial in men's health, with specific recommendations for ED, BPH, and prostate cancer management.
research Skin Care Properties of Grape Seed Polyphenols, a By-Product of the Winery Industry
Grape seed extract is good for skin care, with antioxidant, anti-inflammatory, and anti-cancer effects.
research News in Brief
Researchers discovered potential origins and new treatments for skin cancer, including biomarkers for melanoma and therapies that reduce tumor growth.
research Inhibition of Metastatic Squamous Cell Carcinoma Development in Protein Kinase C Epsilon Transgenic Mice by Alpha-Difluoromethylornithine with Hair Follicle Degeneration and Hair Loss
Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.
research Oral Presentation Abstracts
The conclusions are: fecal short-chain fatty acids may help prevent cancer, fiber intake can reduce obesity, weight loss is hard for obese people, low BMI cancer patients are more prone to chemotherapy side effects, intermittent fasting benefits gut health, cherry laurel has health benefits in rats, certain gene variations can increase stress in hair loss patients, fecal acids can affect blood sugar levels, cold agglutinin can affect blood test results in autoimmune patients, and people with Crohn's disease have higher levels of a certain chemical in their blood.
research Anthocyanin as Colorectal Anticancer: A Brief Review
Anthocyanins from fruits and vegetables may help prevent and treat colorectal cancer safely.
research Tumor Development in Lynch Syndrome: Genes Load the Gun, Lifestyle Pulls the Trigger?
Lifestyle factors like BMI at young adulthood can increase cancer risk in women with Lynch Syndrome, but diet and height don't seem to affect this risk.
research 5-Alpha Reductase Inhibitors Use in Prostatic Disease and Beyond
5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.
research Progress on Study of Pharmacological Effects of Procyanidins
Procyanidins may have antioxidant, heart health, cancer-fighting, anti-inflammatory, anti-diabetic, liver-protective, and other health benefits with high efficiency and low toxicity.
research Cyclooxygenases in the Skin: Pharmacological and Toxicological Implications
Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
research The Clinical Applications of Five-Alpha Reductase Inhibitors
Five-alpha reductase inhibitors, like finasteride and dutasteride, can treat enlarged prostates, improve urination, reduce need for prostate surgery, and lower the risk of prostate cancer, but may increase the risk of higher grade prostate cancer. They can also treat male pattern baldness.
research Using 5 Alpha Reductase Inhibitors Safely: What Primary Care Physicians Need to Know
5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.
research The Role of Dutasteride in the Treatment of Benign Prostatic Obstruction and Related Conditions
Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.
research Sulforaphane Mobilizes Cellular Defenses That Protect Skin Against Damage by UV Radiation
Sulforaphane from broccoli can help protect skin from sun damage.
research Antioxidants in Dermatology
Antioxidants can benefit skin health but should be used carefully to avoid negative effects.
research Persistent Sexual Dysfunction and Depression in Finasteride Users for Male Pattern Hair Loss: A Serious Concern or Red Herring?
Finasteride, a hair loss drug, may cause sexual dysfunction and depression, but these effects are usually temporary and the drug is generally safe. More research is needed.
research Case-Only Trees and Random Forests for Exploring Genotype-Specific Treatment Effects in Randomized Clinical Trials with Dichotomous End Points
Case-only trees and random forests improve predictions of treatment effects in clinical trials.
research Gynecomastia After Finasteride Therapy
Finasteride may cause breast enlargement, low testosterone a risk factor.
research Evolution and Function of Vitamin D
Vitamin D is essential for bone health and may reduce risks of several diseases.
research Steroidal 5α-Reductase and 17α-Hydroxylase/17,20-Lyase (CYP17) Inhibitors Useful in the Treatment of Prostatic Diseases
Certain drugs that block specific enzymes can help treat prostate diseases.