June 2024 in “British Journal of Dermatology” This study reported a gap between podiatrists' frequent encounters with suspicious pigmented foot lesions and their lack of formal melanoma detection training, highlighting a need for improved education and referral pathways.
April 2009 in “The FASEB Journal” This study demonstrated that a keratin gel promotes nerve regeneration across critical defects in rabbit models, showing improved nerve conduction and muscle action potential compared to control treatments.
November 2025 in “Journal of Investigative Dermatology” Mesenchymal stiffness affects sweat gland cell development.
107 citations
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May 1999 in “Archives of Dermatological Research” In this study, the immunohistochemical and lectin binding profiles of basal cell carcinoma closely resembled those of the outer root sheath of vellus hair follicles, suggesting a potential histochemical relationship.
81 citations
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June 2014 in “Cold Spring Harbor perspectives in medicine” This article discusses recent advances in understanding the mechanisms of tactile end organs in the epidermis and hair follicles from studies of mouse hairy skin, but it reports no new clinical results.
15 citations
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August 2013 in “Stem Cells and Development” This study proposes a two-step method that may enhance the generation of stem-like epidermal cells with superior proliferation and differentiation potential for skin regeneration.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that fibrosis-associated trochanters in central centrifugal cicatricial alopecia are enriched with hair follicle stem cells and may indicate a disrupted stem cell niche contributing to scarring.
April 1977 in “Pediatric Research” 13 citations
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January 1985 in “International Journal of Dermatology” This study compared trichostasis spinulosa with keratosis pilaris and eruptive vellus hair cysts, finding differences in lesion distribution and microscopic appearance.
January 2018 in “Elsevier eBooks” Different nail disorders are treated by targeting their specific causes and using appropriate medications or protective measures.
8 citations
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March 2009 in “Differentiation” The study demonstrated that bulge stem cells from rat vibrissa follicles respond to adult dermal papilla signals, inducing hair bulb formation and regenerating hair structures in vivo.
January 2024 in “Revista del Centro Dermatológico Pascua” In this case report, a 24-year-old male with acquired distal trichorrhexis nodosa showed significant improvement after avoiding harmful hair treatments and using a repair shampoo alongside biotin and zinc supplements.
2 citations
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January 2019 in “Acta dermato-venereologica”
17 citations
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January 2010 in “Acta Dermato Venereologica” This report details a case of a 43-year-old woman developing yellowish papular eruptions alongside typical acneiform skin reactions on her cheeks and chest following a switch from cetuximab to panitumumab treatment.
This study found that encapsulating dermal papilla spheroids in alginate hydrogel with extracellular matrix proteins increased alkaline phosphatase activity, suggesting an enhanced manipulation of dermal papilla activity.
3 citations
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March 2013 in “American Journal of Dermatopathology” This study found that ossification in trichilemmal cysts may be more common than previously thought, often associated with cyst wall rupture, and reports a novel case of ossifying TC with extramedullary hematopoiesis.
August 2015 in “MOJ proteomics & bioinformatics” This study suggests that epithelial-derived pop-up keratinocytes (ePUKs) may improve regenerative medicine applications due to their specific phenotype and increased expression of proteins involved in regulating cellular movement and wound healing.
September 2019 in “Journal of Investigative Dermatology” This study found that using human induced pluripotent stem cells (iPSC) carrying the causal mutation of Epidermolysis Bullosa simplex provides a robust model for understanding its molecular mechanisms and testing potential therapeutic targets.
7 citations
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September 1980 in “Zoological Journal of the Linnean Society” This study observed that dermal dendritic cells migrate to the epidermis in mouse tail and back skin, correlating with changes in epidermal physiology like ortho- and parakeratosis.
October 2025 in “The Sri Lanka Journal of Dermatology” This case report highlights the diagnostic challenge of inverted follicular keratosis, emphasizing the importance of histopathology for accurate differentiation from malignancies.
This study explored the carbohydrate composition of plasma cell membranes in human embryonic epidermis over various gestational ages and found specific patterns that may inform future diagnostic and therapeutic approaches for dermatoses.
1 citations
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February 2002 in “The Lancet” Keratinocytes might turn into stem cells, but more research is needed to confirm this.
April 2024 in “Materials today bio” In this study, the researchers developed a novel wound dressing incorporating copper-doped calcium silicate and curcumin, which significantly promoted nerve and blood vessel regeneration in deep burn wounds, emphasizing the crucial role of bioactive chelation in neuralized skin repair.
3 citations
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January 2018 in “Skin Appendage Disorders” This case report describes two instances of habit tic nail deformities associated with alopecia areata.
1 citations
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September 2005 in “Oncology times” In this study, wearing a frozen glove during docetaxel chemotherapy reduced nail problems in patients' gloved hands compared to unprotected hands, with onycholysis absent among protected hands.
October 2010 in “EUR Research Repository (Erasmus University Rotterdam)” This case report describes the successful treatment of scedosporiosis-induced cellulitis with voriconazole and intermittent pneumatic compression in a 72-year-old Portuguese woman.
106 citations
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April 1986 in “British Journal of Dermatology” This study found that dermal papilla cells from human hair follicles form multi-layered aggregates when cultured in vitro, contrasting with the monolayer growth of dermal fibroblasts.
18 citations
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January 1992 in “Dermatology” This case report details atrichia with papular lesions in a 4-year-old girl, highlighting specific histological findings on her scalp and other affected areas.
10 citations
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August 2016 in “Dermatology Online Journal” This article describes cutaneous reactions including keratosis pilaris-like eruptions in a patient on nilotinib for chronic myelogenous leukemia, emphasizing the importance of accurately classifying such eruptions.
March 2021 in “Cell stem cell” This study found that actomyosin contractility in suprabasal keratinocytes influences the proliferation and differentiation of epidermal stem/progenitor cells by acting as a niche element in the skin.