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Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.

Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

The document concludes that validated methods are needed to ensure the quality of fluconazole drugs and that new antifungal medications are necessary due to safety and resistance concerns.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Minoxidil helps prevent hair loss from chemotherapy in rats.

Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Germacrone in Curcuma aeruginosa extract degrades at high temperatures but is stable in certain solutions and unaffected by pH levels.

Hair and scalp pain is more common and severe in breast cancer patients on chemotherapy than those on tamoxifen.

Certain genes controlled by OVOL1 are crucial for creating new hair follicles.

Researchers made two new compounds that could be used for medicine.

Most adult women with PCOS in Port Harcourt, Nigeria, have high levels of bad fats in their blood, especially younger women.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

The bark of Myrica rubra contains compounds that can block testosterone effects and might help prevent hair loss.

Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

α-spinasterol from Melandrium firmum can help reduce prostate enlargement.

New treatments for hair loss show promise, but more development is needed, especially for tough cases.

Hair loss in women can be slowed with treatment, but more research needed for better solutions.

Dutasteride works better than finasteride for preventing and treating prostate cancer.

Healthcare claims databases can help monitor drug safety, but may report adverse events differently than direct surveillance.

Most HIV patients develop skin symptoms that can indicate the stage of their disease.

Reflectance confocal microscopy is useful for diagnosing scalp melanomas, which have features similar to those on the trunk.