January 2018 in “VCU Scholars Compass (Virginia Commonwealth University)” In this study using Xenopus laevis embryos, reduced levels of the desmosomal protein desmoplakin led to defects in epidermal and cardiac structures, suggesting its crucial role in tissue integrity.
48 citations
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March 2010 in “PloS one” This study found that the co-ablation of C/EBPalpha and C/EBPbeta in adult mouse skin disrupted sebocyte differentiation and epidermal homeostasis, highlighting their critical roles in these processes.
6 citations
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May 2012 in “Archives of Dermatological Research” This study reports a novel missense mutation in the HR gene in a 68-year-old Hungarian woman with alopecia universalis and limb deformities, suggesting a need for further research on its role in these conditions.
8 citations
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June 2012 in “PloS one” This study found that the Plcd3(mNab) mutation in mice worsens the alopecia caused by Plcd1 loss, suggesting synergistic effects between Plcd1 and Plcd3 on hair follicle health.
22 citations
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July 2019 in “PLOS ONE” This study found that lymphatic vessels promote hair follicle growth in mice and may represent new therapeutic targets for hair loss conditions.
16 citations
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September 2017 in “PLoS ONE” This study hypothesizes that a mummified 19th Century girl in San Francisco died of severe undernourishment potentially due to a bacterial-borne disease, highlighting historical health challenges mitigated by modern sanitation and medicine.
4 citations
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December 2021 in “Experimental and Therapeutic Medicine” This article describes adult female acne as a complex condition affected by genetic, hormonal, and environmental factors, with hormonal therapies highlighted as particularly valuable for treatment.
2 citations
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August 2020 in “International Journal of Cosmetic Science” This study suggests that Lindera strychnifolia root extract may help restore a healthy microbial balance on the scalp in men with androgenetic alopecia after 83 days of treatment.
1 citations
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March 2015 in “Journal of the European Academy of Dermatology and Venereology” This letter to the editor shares a case study of lentiginous melanoma that appears clinically malignant but histopathologically benign, involving the BRAFV600R mutation.
1 citations
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February 2025 in “Cell Biology International” This study found that both dental pulp-derived and hair follicle-derived mesenchymal stem cells showed similar stemness properties and differentiation potential, but hair follicle-derived cells exhibited superior differentiation into insulin-producing cells, suggesting their potential for autologous stem cell therapy in diabetes.
April 2025 in “Cellular and Molecular Biology” This study found that human dermal stem/progenitor cells demonstrated greater proliferation and differentiation potential than hair follicle dermal papilla cells, which showed increased expression of hair regeneration markers.
January 2005 in “Yaowu fenxi zazhi” This study concluded that domestic and imported finasteride tablets are bioequivalent, with no significant differences in their pharmacokinetics among healthy volunteers.
In this study, researchers found that crude extracts from Avicennia marina and its component avicequinone C inhibit mechanisms contributing to androgenic alopecia in vitro, including 5α-reductase activity and DHT-AR interactions, potentially promoting hair growth and delaying the catagen phase in human dermal papilla cells.
272 citations
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September 2001 in “Journal of Biological Chemistry” This study cataloged human type II hair keratins, detailing their expression and differentiation roles in hair follicles and comparing them with type I keratins to explore keratin-pairing principles.
9 citations
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April 2018 in “Canadian Journal of Animal Science” This study found that LEF-1 expression influences dermal papilla cells' proliferation through Wnt signaling, impacting the potential for cashmere yield improvement.
2 citations
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September 2020 This Mendelian randomization study reports that lifelong increased free testosterone in males was associated with improved bone mineral density and body composition but increased risks of prostate cancer, hypertension, and several other conditions.
January 2024 in “Journal of Microorganism Control” In this study, researchers found that an antibacterial toner can penetrate keratin and sebum plugs and exhibits bactericidal effects against Cutibacterium acnes, as evidenced by a decrease in viable cell counts within artificial plugs inoculated with the bacteria.
December 2013 in “미용예술경영연구” This study found that scalp treatments improved hair density and reduced the number of telogen bulbs in patients with Telogen Effluvium.
140 citations
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December 2017 in “Journal of Controlled Release” This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.
86 citations
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June 2017 in “Anais Brasileiros de Dermatologia” This review discusses the role of antioxidants in managing oxidative skin damage and reports no new results, emphasizing the need for understanding their mechanisms, limitations, and risks for safe use.
72 citations
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March 2013 in “Primates” In this study, the isotopic fractionation between tissues and diets of captive Japanese macaques was quantified, particularly noting hair's response to diet changes in controlled conditions, but these findings underscore the complexity of reconstructing long-term dietary history.
3 citations
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March 2015 in “Biomolecules & Therapeutics” In this study, BP201, derived from porcine lung phospholipids, promoted hair growth in mice, especially when combined with minoxidil, and increased hair follicle numbers and dermal papilla cell proliferation.
This review discusses potential causes and diagnostic tools for alopecia in guinea pigs and highlights the need to evaluate diet and housing, but it reports no original findings.
1 citations
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August 2012 in “Pediatrics in review” This paper reviews various vitamin deficiencies, including vitamin D, and highlights their potential health impacts. It does not report new research findings but discusses current recommendations and risks associated with these deficiencies.
1 citations
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January 2023 in “Journal of research in pharmacy” This study found that the methanolic extract of Carduus adpressus exhibited strong antibacterial, antioxidant, and wound-healing activities, suggesting its potential use in developing wound-healing agents.
April 2025 in “Journal of Cosmetic Dermatology” This study suggests potential causal associations between certain lipid levels, specifically HDL-C and triglycerides, and alopecia areata, highlighting the importance of lipid management as a therapeutic target.
In an animal study, researchers observed that a Chromolaena odorata layered-nitrile rubber transdermal patch significantly improved wound contraction, protein, hexosamine, and uronic acid levels, and collagen deposition in healing excision wounds in rats compared to a control group with an empty patch.
November 2022 in “Journal of Investigative Dermatology” This study found that innate lymphoid cells-type 1 can induce alopecia areata characteristics in human hair follicles both ex vivo and in vivo, challenging the view of it as solely an autoimmune disease driven by CD8+ T cells.
November 2020 in “Journal of The American Academy of Dermatology” This study investigated the use of spironolactone in patients with estrogen-dependent cancers, aiming to determine if it is linked to increased cancer recurrence risk, but results are not reported.
April 2019 in “Journal of the Endocrine Society” In this case report, significantly elevated testosterone levels were documented in a young female with Type A Insulin Resistance Syndrome, marking a clinical finding beyond what is typically associated with the disorder's known mutations.