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Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Platelet-rich plasma (PRP) is a cheap and easy treatment for hair loss, but not suitable for everyone. It also helps in healing ulcers, rejuvenating skin, and improving hair transplants.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Stem cells from hair follicles can safely treat hair loss.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

EVAL membranes help create cell structures that can regrow hair follicles.

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Some women with common hair loss may develop permanent hair loss.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Msx2 and Foxn1 are both crucial for hair growth and health.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Improving the environment and cell interactions is key for creating human hair in the lab.

Adult mice can grow new hair from skin wounds.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.