December 2025 in “Dermatological Health” This case report describes how a 23-year-old woman experienced eyebrow thinning and hair loss linked to cosmetic use, with diagnostic tests confirming follicular damage. Discontinuing the product led to eyebrow regrowth, highlighting potential risks from cosmetics and the value of non-invasive diagnostics for evaluation.
221 citations
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July 2012 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that the circadian clock in mouse skin regulates cell proliferation and affects sensitivity to UVB-induced DNA damage, with potential implications for understanding human skin cancer risk.
68 citations
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April 1965 in “General and Comparative Endocrinology” This study found that the pituitary gland is crucial for normal pelage color cycles in weasels, with certain hormones influencing regrowth of pigmented or white hair after molting.
34 citations
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January 1943 in “Endocrinology” In this study, adrenalectomy in rats on a diet lacking certain vitamin B components reversed fur graying and enhanced hair growth.
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that overexpression of β-catenin in bipotent Schwann-cell precursors promotes melanocyte development in limb areas by inducing MITF and repressing FoxD3, especially during a specific developmental timeframe.
4 citations
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January 1982 in “Neuroendocrinology” This study found that pimozide, d-butaclamol, and pituitary pars intermedia grafts darken hair color in agouti C3H Avy mice, suggesting dopaminergic inhibition influences peptide-controlled hair color cycling.
10 citations
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June 2009 in “Acta Biochimica Polonica” This study found that splenic melanosis in C57BL/6 mice is associated with synchronized skin melanization during hair cycles, but decreases with age.
10 citations
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August 2023 in “Animals” In this study, researchers examined chicken feather follicle tissues from differently colored chickens and found that the genes SLC45A2 and GPNMB are involved in promoting melanin deposition, which enriches understanding of the genetic mechanisms affecting feather color.
3 citations
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November 1983 in “BMJ” 2 citations
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April 1984 in “BMJ” 1 citations
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June 2024 in “BMJ Paediatrics Open” In this study, the prevalence of skin changes in hospitalized children with acute illness, categorized by nutritional status, was lower than previously reported, and the SKORDoK tool was less reliable for dermatological assessment using photographs.
1 citations
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December 2011 in “EFSA Journal” This opinion from the EFSA Panel concludes that the health claim regarding spermidine prolonging the anagen phase of the hair cycle does not meet regulatory criteria as it is related to disease treatment.
This review evaluates the clinical efficacy of platelet-rich plasma therapy in dermatology, highlighting recent research findings and discussing its potential and limitations without reporting new clinical results.
March 2026 in “Oral Presentations” This abstract reports pooled safety data from the WILLOW study for participants with cutaneous lupus erythematosus and systemic lupus erythematosus but does not provide new findings.
March 2026 in “Oral Presentations” This study identified hemoglobin level as the strongest biological predictor of fatigue in systemic lupus erythematosus patients, highlighting its association with disease activity and systemic inflammation.
This study found that sodium valproate improved seizure control in children with epilepsy, with increased weight gain being the most common side effect reported.
2 citations
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July 2023 in “International Journal of Molecular Sciences” This study found that applying a formulation derived from Bacopa procumbens significantly promoted hair growth, pigmentation, and follicular cycle acceleration in mice compared to minoxidil, potentially offering a new therapeutic approach for hair health.
109 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.
27 citations
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January 1995 This study found that higher melanin concentration in black hair offers photoprotection against sunlight-induced protein damage in the cortex, whereas the cuticle experiences similar photodamage regardless of hair pigmentation.
June 2025 in “Clinical and Experimental Dermatology” This report describes a rare case where a 76-year-old man's grey scalp hair unexpectedly regained its original orange to brown color after he underwent radiotherapy for squamous cell carcinoma, suggesting possible implications involving hair follicle melanocytes and radiation effects.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that hemoglobin α expression in the epidermis is induced by oxidative stress and may function as an antioxidant, contributing to skin barrier function.
2 citations
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May 2019 in “International Journal of Molecular Sciences” This study suggests that in gp91phox-knockout mice, tranexamic acid administration led to brown hair by increasing MGRN1 and collagen XVII levels, while the retention of black hair appears to rely on the gp91phox/ROS/IL-1β/TGF-β pathway.
November 2025 in “Journal of Clinical Practice and Medical Research” This study analyzed techniques to create the popular "sun-kissed" hair look on dark-to-medium blonde (Level 5–6) tones, concluding that a 2–3 level differential, targeted placement across three cranial zones, and acidic glossing are essential for optimal results.
54 citations
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December 1999 in “Journal of Investigative Dermatology Symposium Proceedings” This study observed that the development of the pars intermedia in long-tailed macaques is closely associated with changes in skin pigmentation during pre- and postnatal periods through melanocyte-stimulating hormone and ACTH activity.
October 2025 in “Phytochemistry Letters” November 2025 in “Journal of Investigative Dermatology” Dark skin has stronger barriers and structure due to specific gene activity.
17 citations
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May 2012 in “Journal of dermatology” This letter to the editor compares the efficacy and safety of bimatoprost 0.03% with minoxidil 3% for eyebrow enhancement but does not report any study results.
22 citations
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December 2014 in “Naunyn-Schmiedeberg's Archives of Pharmacology” This study found that baicalin activates Wnt/ß-catenin signaling in human dermal papilla cells, increasing alkaline phosphatase expression, growth factor expression, and promoting hair growth in mice.
January 2008 in “Linchuang pifuke zazhi” This study found that betamethasone increased tyrosinase activity and melanin content in amelanotic melanocytes from human hair follicles, suggesting a potential mechanism for glucocorticoid treatment in vitiligo.