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Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.

Vitamin D and its receptor may help prevent skin cancer.

Hedgehog signaling is crucial for mammary gland development over hair follicles.

Aminopterin was somewhat effective in acute lymphoblastic leukemia in children but did not increase survival time.

PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Bariatric surgery affects skin health, causing both direct complications and changes in existing skin conditions, often related to nutritional deficiencies.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

The research suggests that autophagy-related genes might play a role in causing alopecia areata.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

Researchers found two new genetic variants linked to Alzheimer's disease.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.

Hormonal therapies, like flutamide and cyproterone acetate, are safe and effective for treating adult women's acne, especially those with hormone imbalance or resistant acne.

Porphyra-334 may help reduce wrinkles and promote hair growth.