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Ramania leaf extract is non-toxic but can cause stomach ulcers at high doses.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

Higher prenatal and adult androgen levels are linked to alcohol dependence and withdrawal severity.

TGFβ signaling prevents sebaceous gland cells from producing fats.

Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.

Levodopa for Parkinson's disease might be linked to skin issues like melanoma, but it's unclear if the drug or the disease causes them.

Most dogs with paw inflammation had chronic issues, often due to allergies, and certain breeds were more affected.

A patient developed a severe skin reaction and died after taking hydroxychloroquine for COVID-19.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

A cat with ear infection and skin issues was successfully treated for Demodex mites using imidacloprid and moxidectin.

Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Celiac disease can cause skin problems that may get better with a gluten-free diet.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

Endo-HSE helps grow hair-like structures from human skin cells in the lab.