research Anabolic Effects of Testosterone Are Preserved During Inhibition of 5α-Reductase
Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.
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research Aromatase Deficiency in a Male Patient: Case Report and Literature Review
A male with aromatase deficiency improved bone health with estradiol treatment.
research Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands
Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
research Effects of Lifelong Testosterone Exposure on Health and Disease Using Mendelian Randomization
Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.
research Binding Interactions of Keratin-Based Hair Fiber Extract to Gold, Keratin, and BMP-2
Keratin from hair binds well to gold and BMP-2, useful for bone repair.
research What Is the Rationale for Androgen Therapy for Women?
Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.
research Demethylation of ITGAV Accelerates Osteogenic Differentiation in a Blast-Induced Heterotopic Ossification In Vitro Cell Culture Model
Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
research Therapeutic Effect of Mesenchymal Stem Cells on Histopathological, Immunohistochemical, and Molecular Analysis in Second-Degree Burn Model
Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.
research Adverse Effects of Finasteride: Myths and Realities. An Updated Review
Finasteride can cause sexual dysfunction, sperm changes, and affect bone density and metabolism.
research Parathyroid Hormone Linked to a Collagen Binding Domain Promotes Hair Growth in a Mouse Model of Chemotherapy-Induced Alopecia in a Dose-Dependent Manner
A hormone linked to collagen helps hair grow back in mice after chemotherapy, and may also prevent bone loss.
research Testosterone Treatment in Women: An Overview
Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.
research Osteoanabolic Estrogen Therapy in a Transsexual Man
Adding estrogen increased bone mass in a transsexual man undergoing hormone therapy.
research Androgens and the Menopause
Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.
research The Combined Use of Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells Promotes Healing: A Review of Experimental Models and Future Perspectives
Using Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells together can improve healing, including wound healing, bone regeneration, and hair growth.
research Clinical Benefits and Adverse Effects of Genetically-Elevated Free Testosterone Levels: A Mendelian Randomization Analysis
Higher free testosterone levels can increase bone density and decrease body fat but may raise the risk of prostate cancer, hair loss, and benign prostate enlargement.
research Mouse Models with a Disrupted PTHrP Gene or a Disrupted PTH Gene (PTH−/− Mice)
PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.
research Pilomatricoma With Florid Osseous Metaplasia: A Cytologist’s Perspective
A rare skin tumor with bone formation was successfully removed without recurrence.
research Pyoderma Gangrenosum With Neurofibromatosis: Understanding A Possible Relationship And Identifying Risk With Immunosuppressants
The document suggests doctors should watch for bone marrow suppression and severe hair loss in patients treated with Azathioprine.
research Self-Assembled Peptide Hydrogels in Regenerative Medicine
Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.
research JAMA Dermatology: The Year in Review, 2021
In 2021, JAMA Dermatology published significant findings on skin conditions post-COVID vaccination, melanoma surveillance, atopic dermatitis treatments, and confirmed that sun protection does not harm bone health.
research Vulvovaginitis Due to Bone Structure in the Vaginal Canal of a Spayed Dog: Case Report
A spayed dog with vaginal bone structures causing infection was successfully treated by removing the bones and administering medication.
research Methotrexate, Tacrolimus, Voriconazole: High-Risk Cutaneous Squamous Cell Carcinoma in a 65-Year-Old Man
A 65-year-old man developed a serious skin cancer linked to a drug he was taking for a fungal infection after a bone marrow transplant.
research Review Article: Practical Aspects of Testosterone Deficiency Syndrome in Clinical Urology
Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.
research The Dose-Response of Percutaneous Estradiol Implants on the Skeletons of Postmenopausal Women
Higher doses of oestradiol implants improve bone density in postmenopausal women.
research Review Use of Tisseel, a Fibrin Sealant, for Particulate Graft Stabilization
Tisseel shows promise for bone graft stabilization but needs more clinical trials to confirm its effectiveness.
research Comparison of Mesenchymal Progenitor Cell Coating on MBA and DBM as Biochemical Scaffolds
The demineralized bone matrix scaffold is better for cell attachment than the mineralized bone allograft.
research Androgen Receptor Activation Integrates Complex Transcriptional Effects in Osteoblasts, Involving the Growth Factors TGF-β and IGF-I, and Transcription Factor C/EBPδ
DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
research Platelet-Rich Plasma à la Carte
Platelet-rich plasma (PRP) shows no significant benefit for bone and soft-tissue injuries or wound healing, and its effectiveness may improve with customization.
research The Growth of Human Hair in Nude Mice
Adiponectin reduces inflammation and bone loss in joint replacements.
research Comparison of Allogeneic Stem Cell Transplant Conditioning Regimens in AML, MDS, and CLL
Busulfan/cyclophosphamide and total bone irradiation are equally effective for AML transplants.