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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Lower SHBG levels may increase the risk of PCOS.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

Despite progress, better treatments and understanding are needed for the high rates of long-term issues and deaths linked to eating disorders.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

SHBG may be a useful early indicator and treatment target for PCOS.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Premature hair graying in young men is linked to family history, obesity, and smoking.

Silicon can improve skin and hair health, but more research is needed.

Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.

Raspberry ketone may help grow hair and improve skin elasticity.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.