37 citations
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March 2014 in “Journal of Trace Elements in Medicine and Biology” This study reported that Turkish males with male pattern androgenetic alopecia had significantly lower zinc and copper levels in their hair compared to healthy controls, suggesting these imbalances may play a role in the condition's etiology.
23 citations
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January 2016 in “Journal of Nanjing Medical University” This study found that higher BMI in PCOS patients at a Chinese clinic was associated with functional disorders of androgen excess, suggesting BMI may predict hyperandrogenism in this population.
10 citations
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December 2015 in “International Journal of Dermatology” This study suggests that basal cell carcinoma and trichoblastoma may share differentiation toward the hair follicle, as indicated by strong positivity in CK 15, follistatin, and Bmi‐1 markers.
7 citations
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February 2023 in “Obesity” This study found that women with PCOS were more likely than women without PCOS to have multiple weight-loss attempts and perceive themselves as overweight, regardless of their actual obesity status.
4 citations
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May 2023 in “Pigment Cell & Melanoma Research” In this study, researchers found that deleting the Bmi1 gene in murine melanocytes caused premature hair greying and loss of melanocyte lineage cells, highlighting BMI1's role in protecting melanocyte stem cells from stress and oxidative damage.
1 citations
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December 2021 in “Cureus” This study observed that, among women with PCOS, overweight and obese individuals showed a higher prevalence of skin manifestations, with a significant association found between acne and BMI.
1 citations
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December 2017 in “International Journal of Public Health Science (IJPHS)” This study found no significant difference in obesity rates across various phenotypes of PCOS in high-school girls, but highlights the future health risks associated with hyperandrogenism.
1 citations
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September 2017 in “Journal of Investigative Dermatology” This study reported that introducing the TERT and Bmi1 genes into mouse dermal papilla cells resulted in immortal cells capable of inducing new hair follicles in vivo, and human immortal DPCs were also developed.
1 citations
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March 2022 in “Journal of Dermatological Science” This study concluded that overexpressing TERT and BMI1 in cultured human dermal papilla cells extended their lifespan and enhanced their ability to induce hair growth in mice.
January 2025 in “Journal of Cosmetic Dermatology” This study found that in patients with seborrheic dermatitis, higher BMI and poor nutrition habits, such as increased consumption of bread and margarine, were associated with more severe disease, and these patients also experienced higher anxiety and stress levels compared to healthy controls.
May 2024 in “Journal of trace elements in medicine and biology” In this study, researchers observed that pregnant women who were overweight or obese before pregnancy had lower iron concentrations in serum and hair, as well as lower dietary iron intake, during their first trimester compared to women with normal body weight.
June 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This observational study found that benign and HAIR-AN were the most common acanthosis nigricans types associated with obesity, PCOS, and diabetes, highlighting the need for comprehensive screening in affected individuals.
March 2021 in “Journal of Pakistan Association of Dermatologists” This study found a significant association between higher BMI and severe androgenic alopecia in men.
23 citations
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March 2019 in “Plastic and Reconstructive Surgery – Global Open” This study found that BMI was not a significant factor in predicting surgical complications for transgender patients undergoing penile inversion vaginoplasty, suggesting obese patients can safely undergo gender affirmation surgery.
December 2025 in “IntechOpen eBooks” This source critically examines the limitations of using BMI to assess obesity in women, especially during reproductive, pregnancy, and postmenopausal stages, and discusses more precise alternative methods for evaluating obesity in line with sex-specific healthcare needs.
Higher pre-pregnancy BMI is linked to more stress in mothers and more behavioral problems in two-year-old children.
24 citations
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April 2021 in “BMC women's health” This study found that women with PCOS and high BMI exhibited significantly increased hair growth compared to non-PCOS women, suggesting an additive effect of body weight on this phenotype in PCOS.
May 2024 in “Asian Journal of Medicine and Health” This study explored the relationship between BMI percentiles and clinical severity in pediatric patients with different hemoglobin genotypes, finding significant BMI differences and associations with pain frequency, particularly noting that patients with HbSS experienced more pain than those with HbSC.
January 2024 in “International Journal of Biological and Environmental Investigations” This study found that female students aged 18-21 with PCOS had higher weight compared to those without, though their BMI remained in the normal range.
3 citations
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August 2013 in “Maǧallaẗ ǧāmiʻaẗ al-anbār li-l-ʻulūm al-ṣirfaẗ” This study found that women with polycystic ovary syndrome had significantly lower levels of estradiol and follicle stimulating hormone compared to fertile women, with no significant differences in testosterone and thyroid hormone levels.
October 2023 in “Journal of the Endocrine Society” In this case report, a 21-year-old woman with PCOS and obesity underwent bariatric surgery, leading to significant weight loss and improved hormonal balance, which alleviated her hyperandrogenism symptoms like hirsutism and irregular periods.
3 citations
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August 2025 in “International Journal of Molecular Sciences” This study found that women with PCOS have significantly higher prevalence and levels of thyroid autoantibodies, with these elevated levels suggesting a potential independent autoimmune activation associated with PCOS.
815 citations
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April 2010 in “The Journal of Clinical Endocrinology & Metabolism” This review examines the relationship between polycystic ovary syndrome and cardiovascular disease risk, but reports no new clinical findings; the panel calls for guidelines to prevent CVD in this population.
379 citations
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May 2016 in “Cochrane library” This review concluded that corticosteroids improve muscle strength and function in boys with Duchenne muscular dystrophy over short-term periods, but evidence on prolonging walking ability remains insufficient, and side effects are common.
308 citations
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December 2018 in “PLOS Genetics” This study identified three novel genetic loci associated with PCOS and found similar genetic architecture across different diagnostic criteria, with evidence suggesting genetic links between PCOS and various metabolic and psychological traits.
291 citations
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October 2005 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that rat whisker follicle stem cells can be expanded in culture and transplanted to form functional hair follicles, demonstrating their multipotency and potential for regenerative medicine.
271 citations
,
December 2005 in “New England journal of medicine/The New England journal of medicine” This article discusses evaluation and treatment options for a 19-year-old woman with slowly progressive hair growth and reports no new clinical findings.
221 citations
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January 2014 in “Human Reproduction” This study found that the prevalence of polycystic ovary syndrome was 16.6% with Rotterdam criteria but decreased to 6.3% or 8.5% when using alternative criteria involving antral follicle count or anti-Müllerian hormone.
198 citations
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July 2011 in “Cochrane library” This study found that lifestyle interventions improved body composition, hyperandrogenism, and insulin resistance in women with PCOS, but did not affect glucose tolerance, lipid profiles, or clinical reproductive outcomes.
167 citations
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January 2006 in “Gynecological Endocrinology” This study found that women with polycystic ovary syndrome reported a poorer health-related quality of life compared to women in the general population and patients with other medical conditions.