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Abrocitinib effectively treated severe atopic dermatitis and mild alopecia areata in a 12-year-old boy after dupilumab failed.

Using old drugs for new uses can help treat rare immune deficiencies.

A mutation in the IKZF1 gene causes immune system overactivity, linked to autoimmune diseases like lupus.

Endocannabinoids help control mast cell activity in human skin.

NK cells play a role in skin diseases like eczema and psoriasis.

The L412F variant of TLR3 is linked to skin infections, more viral infections, and autoimmune issues.

Two drugs, ritlecitinib and brepocitinib, improved scalp hair loss condition markers.

A patient developed a severe skin reaction and died after taking hydroxychloroquine for COVID-19.

The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.

Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.

Childhood Alopecia Areata causes hair loss and requires varied treatments, with psychological support being crucial.

Stem-cell therapy shows promise for skin conditions but needs more research.

Some drugs, especially biologics, can cause skin reactions that look like other skin diseases, and stopping the drug usually helps clear up these reactions.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

The document listed medical job ads and guidelines for breast cancer screening.

EGFR inhibitors can cause yellowish skin eruptions.

Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

High androgen levels and genetic factors likely cause Becker's nevus and related symptoms.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

New 5% minoxidil formula safely and effectively treats male hair loss.

Activin A increases inner ear hair cell development, while follistatin decreases it.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Minoxidil foam enters hair follicles and skin for hair growth.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Children with scalp fungal infections need proper diagnosis and treatment, usually with antifungal medications, and newer drugs may offer quicker recovery.

Menopause affects hair and skin; more research needed for treatment.

Hair loss in elderly women is often caused by various factors, including hormonal changes after menopause.

Lupus can look like hair loss from alopecia areata but needs different treatment.

Looking at skin can help find and treat serious diseases early.