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Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Different types of skin cells play specific roles in development, healing, and cancer.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

CDP is crucial for lung and hair follicle cell development.

Latanoprost can make eyelashes longer, thicker, and darker.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Bioprinting could improve wound healing but needs more development to match real skin.

Estrogen therapy can reduce skin aging but has cancer risks.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

PRP treatment helps hair growth and density in androgenetic alopecia patients.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.

The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.