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In this animal study, serum biotin levels and clinical symptoms in gilts suggested that serum biotin could serve as a sensitive indicator of biotin deficiency, and a system to evaluate biotin status was proposed.

This review outlines the various processes activated by the peptide GHK-Cu in tissue remodeling and reports improvements in skin and wound healing but notes a need for further study to fully understand these mechanisms.

This review discusses the role of biotin in enzyme function and its effects on hair, skin, and nail health, noting that significant improvements are mostly seen in people with biotin deficiency, and reports no new clinical results.

This review discusses biotin supplementation for dermatological conditions and highlights the lack of strong evidence supporting its efficacy, as well as the potential for laboratory testing interference.

This study suggests that biotin therapy may be beneficial for individuals with partial biotinidase deficiency, as some developed symptoms later, which resolved with treatment.

In this animal study, applying a combination of inositol-stabilized arginine silicate complex and magnesium biotinate promoted hair growth but not nail growth.

This research investigates apoptosis and bcl 2 expression in hair follicles cultured with and without biotin, but it reports no new results.

This article reviews the potential benefits of GHK-Cu, EAA, and water-soluble propolis for wound healing, skin tightening, and anti-aging effects, but reports no new clinical results.

This case report describes a 5-year-old girl with biotinidase deficiency who had acute visual loss and gait disturbance but no typical symptoms, responding well to biotin therapy.

This review provides an overview of biotin's role in metabolism and the consequences of deficiency but reports no new clinical findings; it highlights that intestinal bacteria usually meet biotin needs.

In this study, biotin supplementation improved biotinidase activity and led to clinical remission in some patients with alopecia areata.

This study investigated the effects of biotin deficiency and adequacy on cell proliferation and DNA synthesis in isolated mohair follicles, particularly focusing on the incorporation of [methyl-3 H]thymidine.

This review discusses biotinidase deficiency, noting that biotin treatment from birth can prevent symptoms, but acknowledges the complexity and need for further understanding due to late-onset cases with varied clinical findings.

This review discusses the role of biotin in metabolism and its dietary requirements, but provides no new experimental findings.

In this case report, a 6-year-old male with biotinidase deficiency experienced marked improvement in dermatological symptoms, including alopecia and periorificial lesions, following biotin treatment.

This case report describes a girl with uncombable hair syndrome who showed significant improvement in hair combability and growth rate after two cycles of oral biotin supplementation.

In this study, the researchers observed that biotin administration in biotin-deficient children with alopecia eliminated certain membrane proteins from their blood, suggesting that biotin might regulate these proteins' expression.

This study identified that biotin ingestion led to interference in immunoassay results, falsely indicating high testosterone and insulin levels in a 28-year-old female patient, thus complicating her clinical assessment and treatment planning until recognized and resolved.

This study found that germ-free mice on a biotin-deficient diet exhibited significant weight loss and severe alopecia, unlike conventional mice on the same diet.

This study found that both GHK-Cu liposome and GHK-Cu promoted hair growth and increased VEGF expression in a mouse model of alopecia.

This case report details a family in Iraq with biotin deficiency, highlighting improved outcomes in surviving children following diagnosis and lifelong biotin supplementation.

This study examined the role of biotin deficiency and adequacy on cell proliferation and DNA synthesis in isolated mohair follicles.

This observational study found that a high-dose biotin regimen of 10,000 mcg/day reduced hair loss and improved hair and scalp conditions in female patients with androgenic alopecia, with effects lasting beyond treatment discontinuation, warranting further investigation into biotin's role in combination therapy.

This case report describes a 2-month-old male with biotinidase deficiency whose seizures and skin symptoms improved dramatically with oral biotin supplementation.

Biotin may help hair and nails grow.

This study reports the cloning and sequencing of two type II hair-specific keratin genes, ghHb1 and ghHb6, located on chromosome 12q13, which are expressed during hair growth.

This study found that Ginkgolide B and bilobalide from Ginkgo biloba increased dermal papilla cell viability and promoted hair follicle growth in mink models by influencing signaling pathways.